New Graphs at the braingraph.org Website for Studying the Aging Brain Circuitry.

ArXiv Pub Date : 2024-12-02
Balint Varga, Vince Grolmusz
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Abstract

Human braingraphs or connectomes are widely studied in the last decade to understand the structural and functional properties of our brain. In the last several years our research group has computed and deposited thousands of human braingraphs to the braingraph.org site, by applying public structural (diffusion) MRI data from young and healthy subjects. Here we describe a recent addition to the {\tt braingraph.org} site, which contains connectomes from healthy and demented subjects between 42 and 95 years of age, based on the public release of the OASIS-3 dataset. The diffusion MRI data was processed with the Connectome Mapper Toolkit v.3.1. We believe that the new addition to the braingraph.org site will become a useful resource for enlightening the aging circuitry of the human brain in healthy and diseased subjects, including those with Alzheimer's disease in several stages.

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在过去的十年中,人们广泛研究了人类脑图(braingraphs)或连接体(connectomes),以了解我们大脑的结构和功能特性。在过去几年中,我们的研究小组通过应用来自年轻健康受试者的公开结构(扩散)核磁共振成像数据,计算并向braingraph.org网站存入了数千个人类braingraph。在此,我们将介绍{tt braingraph.org}网站最近新增的内容,其中包含基于公开发布的OASIS-3数据集的42至95岁健康和痴呆受试者的连接组。弥散核磁共振成像数据由 Connectome Mapper Toolkit v.3.1 处理。我们相信,braingraph.org 网站新增加的内容将成为一个有用的资源,用于揭示健康和患病受试者(包括阿尔茨海默病几个阶段的患者)的人脑老化回路。
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