Cost-benefit analysis of Canada's Prison Needle Exchange Program for the prevention of hepatitis C and injection-related infections.

IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Canadian Medical Association journal Pub Date : 2024-12-15 DOI:10.1503/cmaj.240648
Farah Houdroge, Nadine Kronfli, Mark Stoové, Nick Scott
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Abstract

Background: Needle exchange programs are effective public health interventions that reduce blood-borne infections, including hepatitis C, and injection-related infections. We sought to assess the return on investment of existing Prison Needle Exchange Programs (PNEPs) in Canadian federal prisons and their expansion to all 43 institutions.

Methods: We developed a stochastic compartmental model that estimated hepatitis C and injection-related infections under different PNEP scenarios in Canadian federal prisons. Scenarios projected for 2018-2030 were no PNEP, status quo (actual PNEP implementation 2018-2022, with coverage maintained to 2030), and PNEP scale-up (coverage among people who inject drugs in prison increasing over 2025-2030 to reach 50% by 2030). We calculated the benefit-cost ratio as benefits from health care savings, divided by PNEP costs.

Results: By 2019, PNEPs were implemented in 9 of 43 federal prisons, with uptake reaching 10% of people who injected drugs in prison in 2022. Compared with no PNEP, this was estimated to cost Can$0.45 (uncertainty interval [UI] $0.32 to $0.98) million and avert 37 (UI 25 to 52) hepatitis C and 8 (UI -1 to 16) injection-related infections over 2018-2030, with a benefit-cost ratio of 1.9 (UI 0.56-3.0). Compared with the status quo, the PNEP scale-up scenario cost an additional $2.7 (UI $1.8 to $7.0) million and prevented 224 (UI 218 to 231) hepatitis C and 77 (UI 74 to 80) injection-related infections, with a benefit-cost ratio of 2.0 (UI 0.57 to 3.3).

Interpretation: Every dollar invested in the current PNEP or its expansion is estimated to save $2 in hepatitis C and injection-related infection treatment costs. This return on investment strongly supports ongoing maintenance and scale-up of the PNEP in Canada from an economic perspective.

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加拿大监狱针头交换计划预防丙型肝炎和注射相关感染的成本效益分析。
背景:针头交换计划是有效的公共卫生干预措施,可减少血液传播感染,包括丙型肝炎和注射相关感染。我们试图评估加拿大联邦监狱现有的监狱针头交换计划(PNEPs)的投资回报,并将其扩展到所有43个机构。方法:我们开发了一个随机区室模型来估计加拿大联邦监狱中不同PNEP情景下丙型肝炎和注射相关感染。2018-2030年的预测情景为无PNEP、现状(2018-2022年实际实施PNEP,覆盖范围维持到2030年)和PNEP扩大(2025-2030年期间监狱注射吸毒者的覆盖范围增加,到2030年达到50%)。我们将收益成本比计算为医疗保健节省的收益除以PNEP成本。结果:到2019年,43所联邦监狱中有9所实施了PNEPs,到2022年,PNEPs的使用率达到了监狱注射吸毒者的10%。与没有PNEP相比,估计这将花费0.45加元(不确定区间[UI] 0.32至0.98美元),并在2018-2030年期间避免37例(UI 25至52)丙型肝炎和8例(UI -1至16)注射相关感染,收益成本比为1.9 (UI 0.56-3.0)。与现状相比,PNEP扩大方案额外花费了270万美元(180至700万美元),预防了224例(218至231例)丙型肝炎和77例(74至80例)注射相关感染,效益成本比为2.0(0.57至3.3)。解释:在目前的PNEP或其扩展中每投资1美元,估计可节省2美元的丙型肝炎和注射相关感染治疗费用。从经济角度来看,这种投资回报有力地支持了加拿大PNEP的持续维护和扩大。
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来源期刊
Canadian Medical Association journal
Canadian Medical Association journal 医学-医学:内科
CiteScore
8.30
自引率
4.10%
发文量
481
审稿时长
4-8 weeks
期刊介绍: CMAJ (Canadian Medical Association Journal) is a peer-reviewed general medical journal renowned for publishing original research, commentaries, analyses, reviews, clinical practice updates, and editorials. Led by Editor-in-Chief Dr. Kirsten Patrick, it has a significant impact on healthcare in Canada and globally, with a 2022 impact factor of 17.4. Its mission is to promote knowledge vital for the health of Canadians and the global community, guided by values of service, evidence, and integrity. The journal's vision emphasizes the importance of the best evidence, practice, and health outcomes. CMAJ covers a broad range of topics, focusing on contributing to the evidence base, influencing clinical practice, and raising awareness of pressing health issues among policymakers and the public. Since 2020, with the appointment of a Lead of Patient Involvement, CMAJ is committed to integrating patients into its governance and operations, encouraging their content submissions.
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