Simulation of the temperature distribution of kidney stones induced by thulium fiber laser and Ho: YAG laser lithotripsy.

IF 2.1 4区 医学 Q3 ENGINEERING, BIOMEDICAL Lasers in Medical Science Pub Date : 2024-12-17 DOI:10.1007/s10103-024-04255-0
Khwairakpam Shantakumar Singh, Thangjam Premabati
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Abstract

Simulation studies on temperature distribution in laser ablation help predict ablation rates, laser settings, and thermal damage. Despite the limited number of reported numerical studies on the temperature distribution of kidney fluid, there is no simulation study for kidney stone temperature distribution. We employ a numerical approach to study the kidney stone temperature distribution and predict ablation rates, which is an important parameter for clinical lithotripsy. The study looked at how the thulium fiber laser and the Ho:YAG laser differ in terms of temperature profile and ablation depth of kidney stones like calcium oxide monohydrate. The ablation depth increased from 152.7 µm to 489.7 µm when the TFL laser (operated at 10 Hz repetition rate and 1 ms pulse width) fluence increased from 764 J/cm2 to 1146 J/cm2. Correspondingly, the depth increased from 21 µm to 68 µm for the Ho: YAG laser operated at 3 Hz and 0.22 ms pulse width. We attribute this to an increase in temperature with laser energy. We further investigated the effect of pulse width on ablation depth by considering three different TFL pulse widths: 0.5 ms, 0.75 ms, and 1 ms. There was a decrease in ablation depths from 402.5 µm to 242.6 µm when the pulse width increased from 0.5 ms to 1 ms. Because of lower water absorption coefficients, the Ho:YAG laser (70 mJ/10 Hz) produced a smaller ablation depth and temperature profile than the thulium fiber laser (70 mJ/10 Hz). Experimental results from the literature validated the simulation. We found that the Ho:YAG laser worked better for ablation when it was set to 0.2 J/100 Hz for the Ho:YAG laser and 0.4 J/50 Hz for the TFL laser, which were clinical laser settings that we found in the literature. This indicates that, in addition to laser absorption by water, the laser parameters also significantly influence temperature distribution and ablation.

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铥光纤激光与Ho: YAG激光碎石致肾结石的温度分布模拟。
对激光烧蚀过程中的温度分布进行模拟研究有助于预测烧蚀率、激光设置和热损伤。尽管有关肾液温度分布的数值研究报告数量有限,但还没有针对肾结石温度分布的模拟研究。我们采用数值方法研究肾结石温度分布并预测消融率,这是临床碎石的一个重要参数。这项研究考察了铥光纤激光器和 Ho:YAG 激光器在肾结石(如一水氧化钙)的温度分布和烧蚀深度方面有何不同。当铥光纤激光器(以 10 Hz 重复频率和 1 ms 脉宽运行)的能量从 764 J/cm2 增加到 1146 J/cm2 时,烧蚀深度从 152.7 µm 增加到 489.7 µm。相应地,以 3 赫兹和 0.22 毫秒脉宽运行的 Ho: YAG 激光的深度从 21 微米增加到 68 微米。我们将此归因于温度随激光能量的增加而升高。我们进一步研究了脉冲宽度对烧蚀深度的影响,考虑了三种不同的 TFL 脉冲宽度:0.5 毫秒、0.75 毫秒和 1 毫秒。当脉冲宽度从 0.5 毫秒增加到 1 毫秒时,烧蚀深度从 402.5 微米降至 242.6 微米。由于水的吸收系数较低,Ho:YAG 激光器(70 mJ/10 Hz)产生的烧蚀深度和温度曲线小于铥光纤激光器(70 mJ/10 Hz)。文献中的实验结果验证了模拟结果。我们发现,如果将 Ho:YAG 激光器的功率设定为 0.2 J/100 Hz,将铥光纤激光器的功率设定为 0.4 J/50 Hz(这是我们在文献中找到的临床激光设定值),则消融效果更好。这表明,除了水对激光的吸收外,激光参数对温度分布和消融也有很大影响。
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来源期刊
Lasers in Medical Science
Lasers in Medical Science 医学-工程:生物医学
CiteScore
4.50
自引率
4.80%
发文量
192
审稿时长
3-8 weeks
期刊介绍: Lasers in Medical Science (LIMS) has established itself as the leading international journal in the rapidly expanding field of medical and dental applications of lasers and light. It provides a forum for the publication of papers on the technical, experimental, and clinical aspects of the use of medical lasers, including lasers in surgery, endoscopy, angioplasty, hyperthermia of tumors, and photodynamic therapy. In addition to medical laser applications, LIMS presents high-quality manuscripts on a wide range of dental topics, including aesthetic dentistry, endodontics, orthodontics, and prosthodontics. The journal publishes articles on the medical and dental applications of novel laser technologies, light delivery systems, sensors to monitor laser effects, basic laser-tissue interactions, and the modeling of laser-tissue interactions. Beyond laser applications, LIMS features articles relating to the use of non-laser light-tissue interactions.
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