Transformation gap from research findings to large-scale commercialized products in microfluidic field.

IF 8.7 1区 医学 Q1 ENGINEERING, BIOMEDICAL Materials Today Bio Pub Date : 2024-11-29 eCollection Date: 2024-12-01 DOI:10.1016/j.mtbio.2024.101373
Yuqi Ma, Xiaoyi Sun, Ziwei Cai, Mengjing Tu, Yugang Wang, Qi Ouyang, Xueqing Yan, Gaoshan Jing, Gen Yang
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Abstract

The field of microfluidics has experienced rapid growth in the last several decades, yet it isn't considered to be a large industry comparable to semiconductor and consumer electronics. In this review, we analyzed the entire process of the transformation from research findings to commercialized products in microfluidics, as well as the significant gap during the whole developing process between microchip fabrication in R&D and large-scale production in the industry. We elaborated in detail on various materials in the microfluidics industry, including silicon, glass, PDMS, and thermoplastics, discussing their characteristics, production processes, and existing products. Despite challenges hindering the large-scale commercialization of microfluidic chips, ongoing advancements and applications are expected to integrate microfluidic technology into everyday life, transforming it into a commercially viable field with substantial potential and promising prospects.

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微流控领域从研究成果到大规模商业化产品的转化差距。
在过去的几十年中,微流控领域经历了快速发展,但它并没有被视为可与半导体和消费电子产品相媲美的大型产业。在这篇综述中,我们分析了微流控领域从研究成果到商业化产品的整个转化过程,以及整个发展过程中从研发中的微芯片制造到工业中的大规模生产之间的巨大差距。我们详细阐述了微流控行业的各种材料,包括硅、玻璃、PDMS 和热塑性塑料,讨论了它们的特性、生产工艺和现有产品。尽管微流控芯片的大规模商业化面临诸多挑战,但不断取得的进步和应用有望将微流控技术融入日常生活,使其成为一个具有巨大潜力和广阔前景的商业领域。
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来源期刊
CiteScore
8.30
自引率
4.90%
发文量
303
审稿时长
30 days
期刊介绍: Materials Today Bio is a multidisciplinary journal that specializes in the intersection between biology and materials science, chemistry, physics, engineering, and medicine. It covers various aspects such as the design and assembly of new structures, their interaction with biological systems, functionalization, bioimaging, therapies, and diagnostics in healthcare. The journal aims to showcase the most significant advancements and discoveries in this field. As part of the Materials Today family, Materials Today Bio provides rigorous peer review, quick decision-making, and high visibility for authors. It is indexed in Scopus, PubMed Central, Emerging Sources, Citation Index (ESCI), and Directory of Open Access Journals (DOAJ).
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