Pattern of Uveitis in Northern Vietnam.

IF 2.6 4区 医学 Q2 OPHTHALMOLOGY Ocular Immunology and Inflammation Pub Date : 2024-12-16 DOI:10.1080/09273948.2024.2436633
Hoa Dung Do, Van Trong Pham, Tung Quoc Mai, Son Viet Le, Bahram Bodaghi, Thi Hong Nhung Le, Thi Kim Yen Dao, Hanh Hong Tran
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Abstract

Purpose: To characterize the spectrum of uveitis in patients visiting three tertiary hospitals in Hanoi, Vietnam.

Methods: This study collected prospective and multicenter data from patients diagnosed with uveitis at three tertiary hospitals in Hanoi City, Vietnam, between January 2022 and January 2024. Data on age, sex, clinical and laboratory findings, and etiology were collected.

Results: Of 410 patients included, 54.6% were women. The mean age of patients was 39.9 years. Most cases were unilateral and chronic. Anterior uveitis was the most common case (40%), followed by panuveitis (30%), posterior uveitis (26.1%), and intermediate uveitis (3.9%). Undifferentiated uveitis, accounting for 32%, was the most prevalent form across all anatomical groups. The leading etiologies for anterior uveitis included Posner-Schlossman syndrome (18.5%), cytomegalovirus (CMV)-induced uveitis (11%), and Herpes simplex virus-induced uveitis (8.5%). For posterior uveitis, the primary causes were Vogt-Koyanagi-Harada (VKH) syndrome (17.8%), toxocariasis (10.3%), and toxoplasmosis (6.5%). The identified causes of panuveitis included VKH syndrome (24.4%), Behcet's disease (15.4%), and CMV-induced panuveitis (5.7%). We observed six cases of uveitis associated with Haemophilus influenzae (1.5%) without any concomitant systemic symptoms. In our patient population, the most common complication was cataract (11.2%), followed by uveitic macular edema (11%).

Conclusions: Various uveitis patterns were observed among Vietnamese patients, with non-infectious uveitis being predominant.

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越南北部葡萄膜炎的类型。
目的:分析越南河内三所三级医院患者葡萄膜炎的特征。方法:本研究收集了2022年1月至2024年1月期间在越南河内市三家三级医院诊断为葡萄膜炎的患者的前瞻性和多中心数据。收集了年龄、性别、临床和实验室结果以及病因的数据。结果:纳入的410例患者中,女性占54.6%。患者平均年龄39.9岁。大多数病例为单侧慢性。最常见的是前葡萄膜炎(40%),其次是全葡萄膜炎(30%)、后葡萄膜炎(26.1%)和中葡萄膜炎(3.9%)。未分化葡萄膜炎占32%,是所有解剖类群中最常见的形式。前葡萄膜炎的主要病因包括Posner-Schlossman综合征(18.5%)、巨细胞病毒(CMV)引起的葡萄膜炎(11%)和单纯疱疹病毒引起的葡萄膜炎(8.5%)。后葡萄膜炎的主要病因为Vogt-Koyanagi-Harada (VKH)综合征(17.8%)、弓形虫病(10.3%)和弓形虫病(6.5%)。确定的全葡萄膜炎病因包括VKH综合征(24.4%)、白塞病(15.4%)和巨细胞病毒引起的全葡萄膜炎(5.7%)。我们观察到6例葡萄膜炎与流感嗜血杆菌相关(1.5%),没有任何伴随的全身症状。在我们的患者群体中,最常见的并发症是白内障(11.2%),其次是葡萄膜性黄斑水肿(11%)。结论:越南患者存在多种类型的葡萄膜炎,以非感染性葡萄膜炎为主。
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来源期刊
CiteScore
6.20
自引率
15.20%
发文量
285
审稿时长
6-12 weeks
期刊介绍: Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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