DNA-free base editing in lettuce via in vitro transcribed base editors

IF 9.3 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Integrative Plant Biology Pub Date : 2024-12-18 DOI:10.1111/jipb.13822
Eunbin Lee, Yunsun Kim, Minju Kim, Donghui Lee, Beum-Chang Kang
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Abstract

A newly developed RNA-based adenine and cytosine base editing system achieves targeted and efficient A-to-G and C-to-T conversions in lettuce. This DNA-free base editing method has potential uses in crop breeding and biotechnology.

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利用体外转录碱基编辑器对生菜进行无dna碱基编辑。
新开发的基于rna的腺嘌呤和胞嘧啶碱基编辑系统实现了生菜中A-to- g和C-to-T的靶向和高效转化。这种无dna碱基编辑方法在作物育种和生物技术方面具有潜在的应用前景。
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来源期刊
Journal of Integrative Plant Biology
Journal of Integrative Plant Biology 生物-生化与分子生物学
CiteScore
18.00
自引率
5.30%
发文量
220
审稿时长
3 months
期刊介绍: Journal of Integrative Plant Biology is a leading academic journal reporting on the latest discoveries in plant biology.Enjoy the latest news and developments in the field, understand new and improved methods and research tools, and explore basic biological questions through reproducible experimental design, using genetic, biochemical, cell and molecular biological methods, and statistical analyses.
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