Evaluation of the Effectiveness of Global Tuberculosis Control Strategies at Different Stages and Analysis of Risk Factors: Findings From the Global Burden of Disease 2021.

IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Archivos De Bronconeumologia Pub Date : 2024-12-06 DOI:10.1016/j.arbres.2024.11.017
Jinyi Wu, Pei Xiao, Yue Zhang, Peng Peng
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Abstract

Background: The purpose of this study was to analyze the prevention and control effects of the three-phase global tuberculosis control strategy, and analyze the influencing factors.

Methods: We collected age-standardized incidence, prevalence, and mortality (ASIR, ASPR, and ASDR) data from the Global Burden of Disease Study (GBD 2021) database. Annual percentage change (AAPC) of ASIR, ASPR and ASDR were analyzed by Joinpoint regression. Correlation and decomposition analyses explored related epidemiological factors.

Results: At the global level, in the first phase Directly-Observed Treatment Strategy (DOTS), the annual reduction in incidence was 1.18%, and prevalence was 0.71%. In the second phase Stop TB, the cumulative mortality decrease was 56.44% which met the desired goal. However, the cumulative decrease of prevalence was only 20.45%. In the third phase End TB, annual rate of reduction in mortality was 3.33%, while the annual rate of reduction in incidence was 1.14%. ASPR showed a large decrease in both low socio-demographic index (SDI) and high SDI regions, the decrease in medium SDI region was small, which might be dominated by demographic factors at the DOTS stage, changed to epidemiologic in the Stop TB stage and to aging factors in the End TB stage.

Conclusion: The control of TB morbidity and mortality had a great achievement in all the 3 different phases of the TB control strategy, and a concerted global effort is still needed in phase 3 to reach the END TB goal. TB prevalence control needs to be emphasized, especially in the middle and high SDI areas.

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全球结核病控制战略在不同阶段的效果评估及风险因素分析:2021 年全球疾病负担》的研究结果。
背景:本研究的目的是分析三期全球结核病控制战略的预防和控制效果,并分析影响因素。方法:我们从全球疾病负担研究(GBD 2021)数据库中收集年龄标准化发病率、患病率和死亡率(ASIR、ASPR和ASDR)数据。采用关节点回归分析ASIR、ASPR和ASDR的年变化百分比(AAPC)。相关分析和分解分析探讨了相关流行病学因素。结果:在全球范围内,第一阶段直接观察治疗策略(DOTS)的年发病率下降1.18%,患病率为0.71%。在控制结核病的第二阶段,累计死亡率下降56.44%,达到预期目标。但累计下降率仅为20.45%。在结束结核病的第三阶段,年死亡率降低率为3.33%,年发病率降低率为1.14%。低社会人口指数(SDI)和高社会人口指数(SDI)地区的ASPR下降幅度较大,中等社会人口指数(SDI)地区的下降幅度较小,可能是DOTS阶段人口因素主导,Stop TB阶段流行病学因素主导,End TB阶段老龄化因素主导。结论:结核病发病率和死亡率的控制在结核病控制战略的所有3个不同阶段都取得了巨大成就,在结核病控制战略的第3阶段仍需要全球共同努力,以实现终止结核病的目标。需要强调结核病流行控制,特别是在中等和高SDI地区。
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来源期刊
Archivos De Bronconeumologia
Archivos De Bronconeumologia Medicine-Pulmonary and Respiratory Medicine
CiteScore
3.50
自引率
17.50%
发文量
330
审稿时长
14 days
期刊介绍: Archivos de Bronconeumologia is a scientific journal that specializes in publishing prospective original research articles focusing on various aspects of respiratory diseases, including epidemiology, pathophysiology, clinical practice, surgery, and basic investigation. Additionally, the journal features other types of articles such as reviews, editorials, special articles of interest to the society and editorial board, scientific letters, letters to the editor, and clinical images. Published monthly, the journal comprises 12 regular issues along with occasional supplements containing articles from different sections. All manuscripts submitted to the journal undergo rigorous evaluation by the editors and are subjected to expert peer review. The editorial team, led by the Editor and/or an Associate Editor, manages the peer-review process. Archivos de Bronconeumologia is published monthly in English, facilitating broad dissemination of the latest research findings in the field.
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