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Thoracic Anatomy and Human Evolution: A Respiratory Advantage for Homo sapiens? 胸部解剖与人类进化:智人的呼吸优势?
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/j.arbres.2025.09.006
Markus Bastir , Francisco García-Río
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引用次数: 0
Addressing Neglected ‘Hot Spots’ of Tuberculosis Persistent Transmission: Prisons and Jails 解决结核病持续传播的被忽视的“热点”:监狱和看守所。
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/j.arbres.2025.09.005
Alessandra Bellavia , Selene Manga , Rosella Centis , Emanuele Pontali
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引用次数: 0
Incidental Finding of a Solitary Sternal Plasmacytoma Detected at Lung Cancer Screening With Low-dose CT in a Smoker With HIV Infection 在低剂量CT肺癌筛查中偶然发现的孤立胸骨浆细胞瘤伴HIV感染的吸烟者。
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/j.arbres.2025.10.001
Ana María Alonso Robles , María Jesús Vivancos Gallego , Luis Gorospe Sarasúa
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引用次数: 0
Addressing the Global Challenges of COPD and Asthma: A Shared Vision from the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) and the Global Initiative for Asthma (GINA) 应对慢性阻塞性肺病和哮喘的全球挑战:慢性阻塞性肺病全球倡议(GOLD)和全球哮喘倡议(GINA)的共同愿景
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/j.arbres.2025.10.011
David M.G. Halpin , Refiloe Masekela , Claus F. Vogelmeier , Obianuju B. Ozoh , Alvaro A. Cruz , Helen K. Reddel , Arzu Yorgancıoğlu , Alvar Agusti , on behalf of the Boards of Directors of the Global Initiative for Chronic Obstructive Lung Disease (GOLD), Global Initiative for Asthma (GINA)
GOLD and GINA have a shared purpose in working to improve outcomes for patients with chronic obstructive pulmonary disease (COPD) and asthma. This joint statement is dedicated to Professor Eric Bateman, an inaugural member of the GINA Science Committee and member of the GINA Board, and to Professor Robert Rodriguez-Roisin, a founder and chair of the GOLD board of directors, both recently deceased. Both made invaluable contributions to asthma and COPD research and took a global perspective on the challenges of diagnosis and management. It was partly Professor Bateman's idea that GOLD and GINA should produce a joint statement addressing the similar challenges faced in the prevention, early and accurate diagnosis and management of both COPD and asthma, emphasizing the determination of both organizations to work together to address these issues.
GOLD和GINA在改善慢性阻塞性肺疾病(COPD)和哮喘患者的预后方面有着共同的目标。本联合声明谨献给最近去世的GINA科学委员会首任成员、GINA董事会成员Eric Bateman教授和GOLD董事会创始人兼主席Robert Rodriguez-Roisin教授。两人都对哮喘和慢性阻塞性肺病的研究做出了宝贵的贡献,并对诊断和管理的挑战采取了全球视角。部分是Bateman教授的想法,GOLD和GINA应该发表一份联合声明,解决COPD和哮喘的预防、早期和准确诊断和管理方面面临的类似挑战,强调两个组织共同努力解决这些问题的决心。
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引用次数: 0
Immune-Mediated Hepatocellular Injury Induced by Elexacaftor/Tezacaftor/Ivacaftor Therapy elexaftor /Tezacaftor/Ivacaftor治疗诱导的免疫介导肝细胞损伤。
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/j.arbres.2025.09.003
Cindy Stephania Aponte Guevara, Ester Zamarrón De Lucas, María Concepción Prados Sánchez
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引用次数: 0
Analysis of Effectiveness of Clinical Psychological Care Protocol for Smoking Cessation With Cytisinicline Cytisinicline戒烟临床心理护理方案的有效性分析。
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/j.arbres.2025.08.002
Angela Ramos-Pinedo , Jose Ignacio de Granda-Orive , Maria Isabel Cristóbal-Fernández , Calos Rábade-Castedo , Elia Pérez-Fernández , Paz Vaquero-Lozano , Maria Inmaculada Gorordo-Unzueta , Lourdes Lázaro-Asegurado , Eva de Higes-Martínez , Juan Antonio Riesco-Miranda , Rosa Mirambeaux-Villalona , Gloria Francisco-Corral , Alejandro Frino-García , Jaime Signes-Costa Miñana , Cristina Villar-Laguna , Ana Maria Cicero-Guerrero , Julio Cesar Vargas-Espinal , Teresa Peña-Miguel , Jacobo Sellares , Carlos Andrés Jiménez-Ruiz

Objectives

The main objective was to analyze the short, medium, and long-term effectiveness of a clinical–psychological care protocol for smoking cessation using cytisinicline. Other secondary objectives were evaluate safety and whether the characteristics of smoking, adherence, and the intensity of craving and withdrawal syndrome at 4th week were associated with effectiveness.

Methods

Observational, prospective, multicenter study that includes smokers motivated to quit evaluated in twelve Smoking Cessation Services in Spain.

Results

A total of 337 smokers were studied. Effectiveness of cytisinicline was 68% at the end of treatment, but was reduced to 48.7%, 40.9% and 28.2%, at 3rd, 6th and 12th month of follow up respectively. The measurement of adherence and the intensity of craving by SRC showed statistically significant association with effectiveness at 24th week, RRadj = 2.2 (p < 0.001) and RRadj = 0.87 (p = 0.011) respectively. Common adverse effects (occurring in more than 10% of patients) were: sleep disorders, headaches, dizziness and digestive disorders.

Conclusions

The effectiveness of protocol was 68% at the end of treatment, but was reduced to 48.7%, 40.9% and 28.2% at 3rd, 6th and 12th months respectively. Subjects who met more than 80% of treatment adherence doubled their chances of success at 6th month. For each point of craving intensity, measured by the SRC, at the end of the pharmacological treatment the chances of success at 6th month were reduced by 13%. Cytisinicline was safe.
目的:主要目的是分析使用cytisinicline戒烟的临床心理护理方案的短期、中期和长期有效性。其他次要目标是评估安全性,以及第4周吸烟、依从性、渴望强度和戒断综合征的特征是否与有效性相关。方法:观察性、前瞻性、多中心研究,包括在西班牙12个戒烟服务机构评估吸烟者戒烟动机。结果:共对337名吸烟者进行了研究。治疗结束时,cytisinicline的有效率为68%,但在随访第3、6、12个月时分别降至48.7%、40.9%和28.2%。SRC测量依从性和渴望强度与第24周的有效性有统计学意义,RRadj=2.2 (p)结论:治疗结束时方案的有效性为68%,但在第3、6、12个月时分别降至48.7%、40.9%和28.2%。达到80%以上治疗依从性的受试者在6个月时成功的机会增加了一倍。SRC测量的每一个渴望强度点,在药物治疗结束时,第6个月成功的机会减少了13%。胞昔霉素是安全的。
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引用次数: 0
Are Dipeptidyl Peptidase-1 Inhibitors the Future Anti-inflammatory Treatment in Bronchiectasis? 二肽基肽酶-1抑制剂是支气管扩张症未来的抗炎治疗方法吗?
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/j.arbres.2025.09.002
Pamela J. McShane
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引用次数: 0
CO1 CO1
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/S0300-2896(26)00017-7
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引用次数: 0
The Harms of Vaping: How Clinicians Can Help Patients Quit 电子烟的危害:临床医生如何帮助患者戒烟。
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/j.arbres.2025.09.001
Irina González
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引用次数: 0
Congenital Lung Malformations: A Comprehensive Overview of Current Knowledge—Narrative Review 先天性肺畸形:当前知识叙述综述的综合概述。
IF 9.2 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2026-02-01 DOI: 10.1016/j.arbres.2025.09.021
João Faria Dias , Mariana Borges Dias , Gustavo Rocha
Congenital lung malformations (CLMs) encompass a range of developmental anomalies, including congenital pulmonary airway malformation (CPAM), bronchopulmonary sequestration (BPS), congenital lobar overinflation (CLO), bronchogenic cysts (BC), and bronchial atresia (BA). These lesions present with varying severity, from incidental findings to severe neonatal respiratory distress. Advances in prenatal imaging, such as ultrasound and fetal magnetic resonance image (MRI), have significantly improved early detection, aiding in better management planning.
CLMs arise from abnormalities during specific stages of lung development. CPAMs are categorized by cyst size and histological type, while BPS is characterized by systemic arterial supply. CLO and BA are associated with air trapping and hyperinflation, and BCs are typically fluid-filled, well defined, and compressive. Postnatal diagnosis is based on high-resolution computed tomography (CT) and occasionally MRI for detailed evaluation.
Surgical resection is recommended for symptomatic lesions, while management of asymptomatic cases remains debated. Elective surgery may help prevent complications like infection or rare malignancy, particularly in CPAM Types 1 and 4 and BCs. However, some lesions remain stable or regress, supporting conservative management in selected cases.
Long-term outcomes are generally positive, with children undergoing early resection often maintaining good lung function due to compensatory lung growth, though subtle functional deficits may persist. Risk stratification using imaging and genetic markers, such as DICER1 mutations, is gaining importance for guiding treatment decisions.
Management should be individualized, involving a multidisciplinary approach and shared decision-making with families. Further research is needed to clarify the natural history of CLMs, optimize the timing of interventions, and standardize long-term surveillance strategies.
先天性肺畸形(CLMs)包括一系列发育异常,包括先天性气道畸形(CPAM)、支气管肺隔离(BPS)、先天性肺叶过度膨胀(CLO)、支气管源性囊肿(BC)和支气管闭锁(BA)。这些病变有不同的严重程度,从偶然发现到严重的新生儿呼吸窘迫。产前成像技术的进步,如超声和胎儿磁共振成像(MRI),大大改善了早期发现,有助于更好的管理计划。clm起源于肺发育的特定阶段的异常。cpam以囊肿大小和组织学类型分类,而BPS以全身动脉供应为特征。CLO和BA与空气捕获和恶性膨胀有关,而bc通常充满流体,定义明确,并且是压缩的。产后诊断基于高分辨率计算机断层扫描(CT)和偶尔的MRI进行详细评估。对于有症状的病变推荐手术切除,而对无症状病例的处理仍有争议。选择性手术可能有助于预防并发症,如感染或罕见的恶性肿瘤,特别是在CPAM 1型和4型和bc。然而,一些病变保持稳定或消退,支持在选定的情况下保守治疗。长期结果通常是积极的,由于代偿性肺生长,早期切除的儿童通常保持良好的肺功能,尽管可能存在细微的功能缺陷。利用成像和遗传标记(如DICER1突变)进行风险分层,对于指导治疗决策越来越重要。管理应个体化,涉及多学科方法,并与家庭共同决策。需要进一步的研究来阐明CLMs的自然历史,优化干预时机,并规范长期监测策略。
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引用次数: 0
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Archivos De Bronconeumologia
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