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Archivos De Bronconeumologia最新文献

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The In-between: Time to Talk About Bronchiectasis in Adolescents and Their Transition to Adult Care 两者之间:是时候谈谈青少年支气管扩张症及其向成人护理的过渡了。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.09.001
Letizia Traversi , Laura Garriga-Grimau , Antonio Moreno-Galdó , Eva Polverino
Paediatric and adult bronchiectasis patients have been addressed in the literature as two different populations due to several differences, but there is insufficient evidence to understand how and when disease characteristics really change along patients’ lifespan. This lack of knowledge is evident in all aspects of the transition: insufficient data is available about radiology, lung function, microbiology and treatment, and only limited information is currently available about changes in clinical presentation and psychosocial aspects. For instance, symptoms seem to improve during the third and fourth decades of life, a period sometimes referred to as the “honeymoon phase”. However, adolescents with bronchiectasis have poorer quality of life than healthy peers, suggesting, therefore, potential disease underestimation at this age.
This scarcity of data most likely hinders the design of appropriate evidence-based transition protocols, ultimately limiting our ability to understand the factors driving disease progression and how to prevent it.
Nowadays it is crucial to raise awareness about this neglected aspect of bronchiectasis care, and fill this cultural and scientific gap by joining forces between pediatricians and adult physicians, to understand and stop disease progression and, lastly, to provide the best possible care to our patients in all phases of their lives.
由于儿童支气管扩张症和成人支气管扩张症患者存在一些差异,因此在文献中将其作为两个不同的人群来研究,但目前还没有足够的证据来了解疾病特征在患者生命周期中如何以及何时发生真正的变化。这种知识的匮乏体现在疾病转变的各个方面:放射学、肺功能、微生物学和治疗方面的数据不足,目前关于临床表现和社会心理方面变化的信息也很有限。例如,在生命的第三和第四个十年,症状似乎有所改善,这一时期有时被称为 "蜜月期"。然而,患有支气管扩张症的青少年的生活质量比健康的同龄人要差,这表明在这个年龄段可能存在疾病低估的情况。数据的匮乏很可能会阻碍设计适当的循证过渡方案,最终限制我们了解疾病进展的驱动因素以及如何预防疾病的能力。如今,至关重要的是要提高人们对支气管扩张症护理中这一被忽视的方面的认识,并通过儿科医生和成人医生之间的合作来填补这一文化和科学空白,从而了解并阻止疾病进展,最后在患者生命的各个阶段为其提供尽可能最好的护理。
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引用次数: 0
Is Cricothyroid Membrane Puncture for Topical Anesthetic Administration in Flexible Bronchoscopy and EBUS/TBNA Safe for the Patient? 在柔性支气管镜和EBUS/TBNA中穿刺环甲膜给药对患者安全吗?
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.12.001
María Sánchez-Samblancat, Dario Alexander Cruz-Chamorro, Selene Peris-Cuenca, Cristina Luna-Pardo, Raquel Martínez-Tomás, Andrés Briones-Gómez, Enrique Cases-Viedma
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引用次数: 0
Cognitive Decline in Pneumonia: A Neglected Consequence 肺炎的认知能力下降:一个被忽视的后果。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.12.011
Julio A. Ramirez
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引用次数: 0
Sinus Histiocytosis: Diagnosis by Cryo-EBUS 窦组织细胞增生症:冷冻 EBUS 诊断
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.11.013
Ana María Andrés Blanco, Milko Terranova Ríos, Angela Alvarez Suárez
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引用次数: 0
Effect of the Antibody-mediated Immune Responses on COPD, Asthma, and Lung Function: A Mendelian Randomization Study 抗体介导的免疫反应对慢性阻塞性肺病、哮喘和肺功能的影响:孟德尔随机化研究》。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.10.003
Xu Guixing , Liu Yilin , Fan Huaying , Liang Fanrong , Li Dehua

Introduction

The precise cause of antibody-mediated immune responses on chronic obstructive pulmonary disease (COPD), asthma, and lung function remains unclear. We characterized the relationship between antibody-mediated immune responses to COPD, asthma, and lung function, ultimately achieve the prevention or treatment.

Methods

We obtained summary data from published genome-wide association studies, including antibody-mediated immune responses, COPD, asthma, forced expiratory volume in the first second (FEV1), forced expiratory volume (FVC), and FEV1/FVC. Bidirectional two-sample mendelian randomization (MR) analysis was used to assess causal relationships of antibody-mediated immune responses, COPD, asthma, FEV1, FVC, and FEV1/FVC.

Results

A total of 20 antibody-mediated immune responses were identified have a significant causal effect on COPD, asthma, FEV1, and FVC, with six exhibiting reverse causality. Importantly, the results of the five MR analyses were almost identical with respect to the causal effect of anti-polyomavirus 2 IgG seropositivity and varicella zoster virus glycoprotein E and I antibody levels on the risk of COPD, asthma, FEV1, and FVC.

Conclusions

This study contributes to existing knowledge by investigating the causal relationship between antibody-mediated immune responses and respiratory conditions, including COPD, asthma, and lung function, using a two-sample MR design. The key findings can aid in identifying individuals at risk of these conditions and facilitate early prevention and diagnosis.
导言:抗体介导的免疫反应对慢性阻塞性肺病(COPD)、哮喘和肺功能影响的确切原因仍不清楚。我们描述了抗体介导的免疫反应与慢性阻塞性肺病、哮喘和肺功能之间的关系,最终达到预防或治疗的目的:我们从已发表的全基因组关联研究中获取了汇总数据,包括抗体介导的免疫反应、慢性阻塞性肺病、哮喘、第一秒用力呼气容积(FEV1)、用力呼气容积(FVC)和 FEV1/FVC。双向双样本泯灭随机化(MR)分析用于评估抗体介导的免疫反应、慢性阻塞性肺病、哮喘、第一秒用力呼气容积(FEV1)、用力呼气容积(FVC)和第一秒用力呼气容积(FEV1/FVC)之间的因果关系:结果:共发现 20 种抗体介导的免疫反应对慢性阻塞性肺病、哮喘、FEV1 和 FVC 有显著的因果关系,其中 6 种表现出反向因果关系。重要的是,在抗多瘤病毒 2 IgG 血清阳性和水痘带状疱疹病毒糖蛋白 E 和 I 抗体水平对慢性阻塞性肺病、哮喘、FEV1 和 FVC 风险的因果效应方面,五项 MR 分析的结果几乎相同:本研究采用双样本 MR 设计,调查了抗体介导的免疫反应与慢性阻塞性肺病、哮喘和肺功能等呼吸系统疾病之间的因果关系,为现有知识做出了贡献。主要发现有助于识别这些疾病的高危人群,促进早期预防和诊断。
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引用次数: 0
Is the Air in the Chest Always of Pulmonary Origin? Pneumopericardium a Rare Pathology 胸部的空气总是来自肺部吗?心包气是一种罕见的病理。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.12.003
Valeria Paulina Pérez Guamán , María Victoria García Gallardo , Paul Andrés Castanier Méndez
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引用次数: 0
A Commentary on ‘Effect of the Antibody-Mediated Immune Responses on COPD, Asthma, and Lung Function: A Mendelian Randomization Study’ 对“抗体介导的免疫反应对COPD、哮喘和肺功能的影响:一项孟德尔随机研究”的评论。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.11.016
Xi Chen , Danpei Li , Zhiqiang Ma
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引用次数: 0
The Importance of ZIP Code-related Average Household Income on the Severity of Respiratory Syncytial Virus Infection in Infants 邮政编码相关家庭平均收入对婴幼儿呼吸道合胞病毒感染严重程度的影响
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.12.002
Rosa Rodríguez-Fernández , Jimena Pérez-Moreno , Felipe González-Martínez , Blanca Toledo del Castillo , Alicia Fernández González , María Isabel González-Sánchez
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引用次数: 0
Circulating Exosomal MicroRNAs and Subclinical Atherosclerosis in Obstructive Sleep Apnea 阻塞性睡眠呼吸暂停患者循环外泌体microrna与亚临床动脉粥样硬化。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.12.005
David Sanz-Rubio , Inmaculada Martín-Burriel , Jorge Rodríguez , Marta Marín-Oto , Abdelnaby Khalyfa , Manuel Sánchez-de-la-Torre , David Gozal , Jose M. Marin
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引用次数: 0
Performance of Home-based High Flow Therapy Devices in Mucus Clearance and Hygrometry 家用高流量治疗装置在粘液清除和湿度测量中的性能。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2025-04-01 DOI: 10.1016/j.arbres.2024.12.009
Roberto Martinez Alejos , Marius Lebret , Gustavo A. Plotnikow , Emeline Fresnel , Maxime Patout
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引用次数: 0
期刊
Archivos De Bronconeumologia
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