Isolation, Structure, and Biological Activities of Exopolysaccharides from Actinomycetes: A Review.

IF 2.3 3区 生物学 Q3 MICROBIOLOGY Current Microbiology Pub Date : 2024-12-18 DOI:10.1007/s00284-024-03999-w
Xiao-Lian Wei, Song-Yi Mo, Rola Ali-Saeed, Hong Zeng
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Abstract

In recent years, exopolysaccharides (EPSs) from actinomycetes have become a significant focus of research due to their diverse biological activities, including antitumor, antiviral, and immunoregulatory effects. This article reviews recent advancements in the study of EPSs from actinomycetes, summarizing findings from existing literature on extraction methods, structural characteristics, and biological activities. Various extraction methods can impact the purity and quality of EPSs obtained from actinomycetes. In addition, EPSs produced by different species of actinomycetes exhibit diverse structures, leading to variations in their biological activities. Future research should focus on optimizing current extraction methods or developing new techniques, exploring the relationship between structural characteristics and biological activities of EPSs, and elucidating their molecular mechanisms of action. Such efforts are essential for the comprehensive study and potential applications of EPSs from actinomycetes.

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放线菌胞外多糖的分离、结构及生物活性研究进展
近年来,放线菌的胞外多糖(EPSs)因其具有抗肿瘤、抗病毒和免疫调节等多种生物活性而成为研究的热点。本文综述了近年来放线菌中eps的研究进展,综述了现有文献在提取方法、结构特征和生物活性方面的研究成果。不同的提取方法会影响从放线菌中获得的eps的纯度和质量。此外,不同种类放线菌产生的eps结构不同,导致其生物活性存在差异。未来的研究应着眼于优化现有的提取方法或开发新的提取技术,探索eps的结构特征与生物活性之间的关系,阐明其作用的分子机制。这些工作对放线菌eps的全面研究和潜在应用至关重要。
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来源期刊
Current Microbiology
Current Microbiology 生物-微生物学
CiteScore
4.80
自引率
3.80%
发文量
380
审稿时长
2.5 months
期刊介绍: Current Microbiology is a well-established journal that publishes articles in all aspects of microbial cells and the interactions between the microorganisms, their hosts and the environment. Current Microbiology publishes original research articles, short communications, reviews and letters to the editor, spanning the following areas: physiology, biochemistry, genetics, genomics, biotechnology, ecology, evolution, morphology, taxonomy, diagnostic methods, medical and clinical microbiology and immunology as applied to microorganisms.
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