Histoplasmosis Associated With Bat Guano Exposure in Cannabis Growers: 2 Cases.

IF 3.8 4区 医学 Q2 IMMUNOLOGY Open Forum Infectious Diseases Pub Date : 2024-12-05 eCollection Date: 2024-12-01 DOI:10.1093/ofid/ofae711
Paulina Sudnik, Patrick Passarelli, Angela Branche, Ellen Giampoli, Ted Louie
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Abstract

Histoplasma capsulatum is a pathogenic dimorphic fungus with evolving epidemiology. Initially described as endemic to the Ohio and Mississippi river valleys, the infection now regularly occurs in central and eastern United States, with cases reported across the entire country. Transmission happens via inhalation of conidia during activities that disturb fungal hyphae. Sporadic cases related to individual exposures now outnumber work-related outbreak cases in the United States. We describe 2 fatal cases of histoplasmosis in Rochester, New York, associated with exposure to bat guano as a fertilizer for cannabis cultivation, including 1 case in which it was commercially obtained.

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荚膜组织胞浆菌(Histoplasma capsulatum)是一种致病性二形真菌,其流行病学不断演变。最初被描述为俄亥俄河和密西西比河流域的地方病,现在这种感染经常发生在美国中部和东部,全国各地都有病例报告。传播途径是在干扰真菌菌丝的活动中吸入分生孢子。在美国,与个人接触有关的零星病例现在已经超过了与工作有关的爆发病例。我们描述了纽约州罗切斯特市的两例组织胞浆菌病死亡病例,这两例病例都与接触作为大麻种植肥料的蝙蝠粪有关,其中一例是通过商业途径获得的。
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来源期刊
Open Forum Infectious Diseases
Open Forum Infectious Diseases Medicine-Neurology (clinical)
CiteScore
6.70
自引率
4.80%
发文量
630
审稿时长
9 weeks
期刊介绍: Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.
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