Integrating C–H activation/2-fold annulation: a modular access to heteroaryl-tethered oxazoloisoquinolinones†

IF 4.2 2区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Chemical Communications Pub Date : 2024-12-12 Epub Date: 2024-12-19 DOI:10.1039/d4cc06123c
Shubhajit Basak , Tripti Paul , Maniya V Nanjegowda , Tharmalingam Punniyamurthy
{"title":"Integrating C–H activation/2-fold annulation: a modular access to heteroaryl-tethered oxazoloisoquinolinones†","authors":"Shubhajit Basak ,&nbsp;Tripti Paul ,&nbsp;Maniya V Nanjegowda ,&nbsp;Tharmalingam Punniyamurthy","doi":"10.1039/d4cc06123c","DOIUrl":null,"url":null,"abstract":"<div><div>A cascade C–H activation/2-fold annulation of 2-aryloxazolines with pyridotriazoles has been achieved employing Rh-catalysis to afford heteroaryl-tethered oxazoloisoquinolinones. The synergistic annulations, functional group tolerance, and late-stage skeletal editing of the bioactive scaffolds are the salient practical features.</div></div>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"61 8","pages":"Pages 1693-1696"},"PeriodicalIF":4.2000,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1359734524027630","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/19 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

A cascade C–H activation/2-fold annulation of 2-aryloxazolines with pyridotriazoles has been achieved employing Rh-catalysis to afford heteroaryl-tethered oxazoloisoquinolinones. The synergistic annulations, functional group tolerance, and late-stage skeletal editing of the bioactive scaffolds are the salient practical features.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
整合 C-H 活化/折叠环化:杂芳基系链噁唑基异喹啉酮的模块化途径
利用铑催化,实现了2-芳基恶唑啉与吡喃三唑的级联C-H活化/2倍环化,得到了杂芳基系结恶唑异喹啉酮。生物活性支架的协同环、功能基耐受性和后期骨骼编辑是其突出的实用特点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Chemical Communications
Chemical Communications 化学-化学综合
CiteScore
8.60
自引率
4.10%
发文量
2705
审稿时长
1.4 months
期刊介绍: ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.
期刊最新文献
A route to asymmetrically substituted secondary phosphines Advances in Functional Photoisomerisable Low-Molecular-Weight π-Gelators Streamlined cofactor recycling with formate for chemo-enzymatic synthesis Total chemical synthesis of pentameric cholera toxin subunit B Large shortening of the lead-lead bond in a diplumbyne upon its one-electron reduction.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1