Shubhajit Basak , Tripti Paul , Maniya V Nanjegowda , Tharmalingam Punniyamurthy
{"title":"Integrating C–H activation/2-fold annulation: a modular access to heteroaryl-tethered oxazoloisoquinolinones†","authors":"Shubhajit Basak , Tripti Paul , Maniya V Nanjegowda , Tharmalingam Punniyamurthy","doi":"10.1039/d4cc06123c","DOIUrl":null,"url":null,"abstract":"<div><div>A cascade C–H activation/2-fold annulation of 2-aryloxazolines with pyridotriazoles has been achieved employing Rh-catalysis to afford heteroaryl-tethered oxazoloisoquinolinones. The synergistic annulations, functional group tolerance, and late-stage skeletal editing of the bioactive scaffolds are the salient practical features.</div></div>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"61 8","pages":"Pages 1693-1696"},"PeriodicalIF":4.2000,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1359734524027630","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/19 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A cascade C–H activation/2-fold annulation of 2-aryloxazolines with pyridotriazoles has been achieved employing Rh-catalysis to afford heteroaryl-tethered oxazoloisoquinolinones. The synergistic annulations, functional group tolerance, and late-stage skeletal editing of the bioactive scaffolds are the salient practical features.
期刊介绍:
ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.