FAAHcilitating recovery in malnourished kids

IF 7.2 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Cell Chemical Biology Pub Date : 2024-12-19 DOI:10.1016/j.chembiol.2024.11.007
Franciscus Chandra , Elaine Y. Hsiao
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Abstract

The molecular underpinnings behind the diet-microbiome-host health relationship are largely undescribed. In a recent issue of Science, Cheng et al.1 uncovered one piece of the puzzle by describing a novel fatty acid amide hydrolase (FAAH) derived from a Faecalibacterium prausnitzii strain that correlated with improved malnutrition recovery. This emphasized the microbiome’s role in supporting recovery from malnutrition.
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促进营养不良儿童的康复
饮食-微生物群-宿主健康关系背后的分子基础在很大程度上未被描述。在最近一期的《科学》杂志上,Cheng等人1通过描述一种新的脂肪酸酰胺水解酶(FAAH),揭开了这个谜题的一部分,这种酶来自于prausnitzii粪杆菌菌株,与改善营养不良的恢复有关。这强调了微生物组在支持营养不良恢复中的作用。
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来源期刊
Cell Chemical Biology
Cell Chemical Biology Biochemistry, Genetics and Molecular Biology-Molecular Medicine
CiteScore
14.70
自引率
2.30%
发文量
143
期刊介绍: Cell Chemical Biology, a Cell Press journal established in 1994 as Chemistry & Biology, focuses on publishing crucial advances in chemical biology research with broad appeal to our diverse community, spanning basic scientists to clinicians. Pioneering investigations at the chemistry-biology interface, the journal fosters collaboration between these disciplines. We encourage submissions providing significant conceptual advancements of broad interest across chemical, biological, clinical, and related fields. Particularly sought are articles utilizing chemical tools to perturb, visualize, and measure biological systems, offering unique insights into molecular mechanisms, disease biology, and therapeutics.
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