Nutrition Interventions in the Treatment of Endometriosis: A Scoping Review

IF 2.9 3区医学 Q3 NUTRITION & DIETETICS Journal of Human Nutrition and Dietetics Pub Date : 2024-12-18 DOI:10.1111/jhn.13411

Samantha C. De Araugo, Jane E. Varney, Amelia J. McGuinness, Colette Naude, Subhadra Evans, Antonina Mikocka-Walus, Heidi M. Staudacher

{"title":"Nutrition Interventions in the Treatment of Endometriosis: A Scoping Review","authors":"Samantha C. De Araugo, Jane E. Varney, Amelia J. McGuinness, Colette Naude, Subhadra Evans, Antonina Mikocka-Walus, Heidi M. Staudacher","doi":"10.1111/jhn.13411","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Pain, poor quality of life (QOL) and gastrointestinal (GI) symptoms are commonly experienced by individuals with endometriosis. Although diet and nutrition supplements are frequently used to manage endometriosis-related symptoms, there is limited understanding of the breadth and quality of research in this field. Our aim was to undertake a scoping review of diet and nutrition supplement intervention studies in people with endometriosis, diagnosed by ultrasound or surgery.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>MEDLINE Complete, Embase, CINAHL and PsycINFO databases were searched for articles published in English from database inception to November 2024. Quality was assessed by two reviewers independently using the Joanna Briggs Institute appraisal tools. In total, 5130 publications were screened and 13 were included.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Among these, five evaluated the effect of diet intervention, one evaluated the effect of a combined diet–supplement intervention and seven evaluated the effect of a nutrition supplement in endometriosis. Overall, there were seven randomised controlled trials (RCTs) (<i>n</i> = 1 diet intervention, <i>n</i> = 6 nutrition supplement), two nonrandomised controlled studies (<i>n</i> = 1 diet intervention, <i>n</i> = 1 combined diet–supplement) and four uncontrolled studies (<i>n</i> = 3 diet intervention, <i>n</i> = 1 nutrition supplement). On the basis of evidence from the RCTs, the low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet improved QOL and GI symptoms, whereas garlic supplements and combination trace element supplements may be beneficial for improving reduced pain symptoms related to endometriosis. The quality of most included studies was poor. Adherence to the interventions was only measured in five studies and only one diet study measured baseline diet.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>High-quality RCTs of diet and nutrition supplement interventions are needed to progress the understanding of whether they should be integrated into the clinical management of endometriosis.</p>\n </section>\n </div>","PeriodicalId":54803,"journal":{"name":"Journal of Human Nutrition and Dietetics","volume":"38 1","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Human Nutrition and Dietetics","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jhn.13411","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Pain, poor quality of life (QOL) and gastrointestinal (GI) symptoms are commonly experienced by individuals with endometriosis. Although diet and nutrition supplements are frequently used to manage endometriosis-related symptoms, there is limited understanding of the breadth and quality of research in this field. Our aim was to undertake a scoping review of diet and nutrition supplement intervention studies in people with endometriosis, diagnosed by ultrasound or surgery.

Methods

MEDLINE Complete, Embase, CINAHL and PsycINFO databases were searched for articles published in English from database inception to November 2024. Quality was assessed by two reviewers independently using the Joanna Briggs Institute appraisal tools. In total, 5130 publications were screened and 13 were included.

Results

Among these, five evaluated the effect of diet intervention, one evaluated the effect of a combined diet–supplement intervention and seven evaluated the effect of a nutrition supplement in endometriosis. Overall, there were seven randomised controlled trials (RCTs) (n = 1 diet intervention, n = 6 nutrition supplement), two nonrandomised controlled studies (n = 1 diet intervention, n = 1 combined diet–supplement) and four uncontrolled studies (n = 3 diet intervention, n = 1 nutrition supplement). On the basis of evidence from the RCTs, the low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet improved QOL and GI symptoms, whereas garlic supplements and combination trace element supplements may be beneficial for improving reduced pain symptoms related to endometriosis. The quality of most included studies was poor. Adherence to the interventions was only measured in five studies and only one diet study measured baseline diet.

Conclusions

High-quality RCTs of diet and nutrition supplement interventions are needed to progress the understanding of whether they should be integrated into the clinical management of endometriosis.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

营养干预治疗子宫内膜异位症：范围综述。

背景：疼痛、生活质量差和胃肠道症状是子宫内膜异位症患者常见的症状。虽然饮食和营养补充剂经常用于治疗子宫内膜异位症相关症状，但对该领域研究的广度和质量的了解有限。我们的目的是对通过超声或手术诊断的子宫内膜异位症患者的饮食和营养补充干预研究进行范围审查。方法：检索MEDLINE Complete、Embase、CINAHL和PsycINFO数据库自建库至2024年11月发表的英文文章。质量由两位评论者使用乔安娜布里格斯研究所的评估工具独立评估。共筛选了5130份出版物，其中13份列入。结果：其中5项评估饮食干预的效果，1项评估联合饮食补充剂干预的效果，7项评估营养补充剂对子宫内膜异位症的影响。总体而言，共有7项随机对照试验（rct）（n = 1项饮食干预，n = 6项营养补充剂），2项非随机对照研究（n = 1项饮食干预，n = 1项联合饮食-补充剂）和4项非对照研究（n = 3项饮食干预，n = 1项营养补充剂）。根据随机对照试验的证据，低发酵低聚糖、双糖、单糖和多元醇（FODMAP）饮食可改善生活质量和胃肠道症状，而大蒜补充剂和联合微量元素补充剂可能有助于改善与子宫内膜异位症相关的疼痛症状。大多数纳入的研究质量较差。只有五项研究测量了干预措施的依从性，只有一项饮食研究测量了基线饮食。结论：需要高质量的饮食和营养补充干预的随机对照试验，以进一步了解是否应将其纳入子宫内膜异位症的临床治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Journal of Human Nutrition and Dietetics 医学-营养学

CiteScore

5.30

自引率

15.20%

发文量

133

审稿时长

6-12 weeks

期刊介绍： Journal of Human Nutrition and Dietetics is an international peer-reviewed journal publishing papers in applied nutrition and dietetics. Papers are therefore welcomed on: - Clinical nutrition and the practice of therapeutic dietetics - Clinical and professional guidelines - Public health nutrition and nutritional epidemiology - Dietary surveys and dietary assessment methodology - Health promotion and intervention studies and their effectiveness - Obesity, weight control and body composition - Research on psychological determinants of healthy and unhealthy eating behaviour. Focus can for example be on attitudes, brain correlates of food reward processing, social influences, impulsivity, cognitive control, cognitive processes, dieting, psychological treatments. - Appetite, Food intake and nutritional status - Nutrigenomics and molecular nutrition - The journal does not publish animal research The journal is published in an online-only format. No printed issue of this title will be produced but authors will still be able to order offprints of their own articles.