Carbon dot embedded hybrid microgel from synthesis to sensing: Experimental and theoretical approach

Abstract

Background

The intellectual progress in fabricating artificial probes for selective appraisal of biologically admissible amino acids has displayed exponential growth in recent era.

Results

Herein, we apprehend the realistic sensing performance of a sulfonamidecinnamaldehyde based Schiff’s base i.e. N-(phenylallylbenzylidene)-4- methylbenzenesulfonohydrazide PBMBS with a customized design to trigger synergistic impact with an effective functional site. PBMBS has an effective fluorescence enhancement aptitude towards tryptophan (Trp) with a detection limit of 5.7 nM. The optimized water/solvent system with a suitable pH range for the quantitative determination of Trp has also been assessed. The fluorescence quantum yields of PBMBS displayed a 31% enhancement in the presence of Trp. Significance:PBMBS based fluorophore was successfully employed to enumerate the Trp content in different water samples with effective recoveries ranging from 97.8% to 104.6%. The effective interpretation of the molecular logic gate framework of PBMBS in the presence of Trp supports the potential prospects of the developed sensor in practical applications.