Inside Back Cover: The careful selection of zwitterionic nanoparticle coating results in rapid and efficient cell labeling for imaging-based cell tracking
Nicholas D. Calvert, Luciana Yu, Olivia C. Sehl, Julia J. Gevaert, Natasha N. Knier, Angelie Rivera-Rodriguez, Clara S. Goulet, Nitara Fernando, Samantha Flood, Carlos M. Rinaldi-Ramos, Paula J. Foster, Adam J. Shuhendler
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Abstract
In the current work, superparamagnetic iron oxide nanoparticles coated with zwitterionic ligands improved cell loading and retention for Magnetic Particle Imaging. The best-performing surface coating enabled high cell uptake with short incubation times and stable in vivo imaging over 7 days. These advancements improve the sensitivity and duration of cell tracking by enhancing nanoparticle loading into a variety of cell types (e609).
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