Comparative effectiveness and safety of Angio-Seal and StarClose vascular closure devices: a systematic review and meta-analysis.

IF 2.4 3区生物学 Q2 MULTIDISCIPLINARY SCIENCES PeerJ Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI:10.7717/peerj.18652

Kun Lai, Jingquan Chen, Qiang Tan, Lan Luo

{"title":"Comparative effectiveness and safety of Angio-Seal and StarClose vascular closure devices: a systematic review and meta-analysis.","authors":"Kun Lai, Jingquan Chen, Qiang Tan, Lan Luo","doi":"10.7717/peerj.18652","DOIUrl":null,"url":null,"abstract":"Objective: This systematic review and meta-analysis aims to evaluate the effectiveness and safety of Angio-Seal and StarClose vascular closure devices (VCDs) in achieving hemostasis after interventional surgery.Methods: Randomized controlled trials (RCTs) and observational studies comparing Angio-Seal and StarClose were identified through systematic searches. Data on vascular closure success rate, complication rates, hematoma formation, pseudoaneurysm, arterial occlusion, and surgical intervention were extracted and pooled using a random effects model.Results: Nine studies met the inclusion criteria, total 5,466 patients. The meta-analysis revealed a slight, statistically significant difference in the success rate of vascular closure in favor of Angio-Seal (risk ratio (RR) 1.05, 95% confidence interval (CI) [1.00-1.09], p = 0.03). No significant difference was found in the overall complication rate, hematoma formation, pseudoaneurysm, arterial occlusion, or surgical intervention.Conclusions: Angio-Seal demonstrated a slightly higher success rate in vessel closure compared to StarClose. Both devices had a comparable safety profile with no significant differences in major complications.","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":"12 ","pages":"e18652"},"PeriodicalIF":2.4000,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11657189/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"PeerJ","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.7717/peerj.18652","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This systematic review and meta-analysis aims to evaluate the effectiveness and safety of Angio-Seal and StarClose vascular closure devices (VCDs) in achieving hemostasis after interventional surgery.

Methods: Randomized controlled trials (RCTs) and observational studies comparing Angio-Seal and StarClose were identified through systematic searches. Data on vascular closure success rate, complication rates, hematoma formation, pseudoaneurysm, arterial occlusion, and surgical intervention were extracted and pooled using a random effects model.

Results: Nine studies met the inclusion criteria, total 5,466 patients. The meta-analysis revealed a slight, statistically significant difference in the success rate of vascular closure in favor of Angio-Seal (risk ratio (RR) 1.05, 95% confidence interval (CI) [1.00-1.09], p = 0.03). No significant difference was found in the overall complication rate, hematoma formation, pseudoaneurysm, arterial occlusion, or surgical intervention.

Conclusions: Angio-Seal demonstrated a slightly higher success rate in vessel closure compared to StarClose. Both devices had a comparable safety profile with no significant differences in major complications.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

angioseal和StarClose血管闭合装置的有效性和安全性比较：一项系统综述和荟萃分析。

目的：本系统综述和荟萃分析旨在评价Angio-Seal和StarClose血管闭合装置（vcd）在介入手术后止血的有效性和安全性。方法：通过系统检索，比较Angio-Seal和StarClose的随机对照试验（rct）和观察性研究。血管闭合成功率、并发症发生率、血肿形成、假性动脉瘤、动脉闭塞和手术干预的数据被提取并使用随机效应模型汇总。结果：9项研究符合纳入标准，共5466例患者。荟萃分析显示，血管封闭成功率与血管封闭成功率有轻微的统计学差异（风险比（RR） 1.05, 95%可信区间（CI） [1.00-1.09], p = 0.03）。在总体并发症发生率、血肿形成、假性动脉瘤、动脉闭塞或手术干预方面没有发现显著差异。结论：与StarClose相比，Angio-Seal在血管闭合方面的成功率略高。两种装置的安全性相当，在主要并发症方面没有显著差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

PeerJ MULTIDISCIPLINARY SCIENCES-

CiteScore

4.70

自引率

3.70%

发文量

1665

审稿时长

10 weeks

期刊介绍： PeerJ is an open access peer-reviewed scientific journal covering research in the biological and medical sciences. At PeerJ, authors take out a lifetime publication plan (for as little as $99) which allows them to publish articles in the journal for free, forever. PeerJ has 5 Nobel Prize Winners on the Board; they have won several industry and media awards; and they are widely recognized as being one of the most interesting recent developments in academic publishing.