Effects of environmentally relevant concentrations of citalopram in freshwater mesocosms

IF 7.6 2区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Environmental Pollution Pub Date : 2024-12-22 DOI:10.1016/j.envpol.2024.125570
Elien Versteegen, Tong Mou, Dailing Wu, Ineke Heikamp-de Jong, Ivo Roessink, Edwin T.H.M. Peeters, Paul J. van den Brink
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Abstract

Increased pharmaceutical usage has led to their widespread presence in aquatic environments, resulting in concerns regarding their potential environmental impacts. Antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs) like citalopram, are frequently detected in European surface waters. Acute laboratory studies have demonstrated that citalopram can inhibit algal growth, immobilise Daphnia magna, and may result in foot detachment (i.e. the inability to adhere to a substrate) in snails. However, research on long-term citalopram exposure is scarce, and our understanding of its effects on aquatic community- and ecosystem-level is limited. Therefore, we investigated the impact of 13-week exposure to 0.01, 0.1, 1, 10 and 100 μg/L citalopram in outdoor freshwater mesocosms, focusing on water quality variables (i.e. pH, dissolved oxygen, electrical conductivity, temperature, algal chlorophyll-a, turbidity) and the structure of aquatic communities, with a special focus on mollusc foot detachment (Lymnaea stagnalis, Planorbis sp. and the total snail population).We found that environmentally relevant citalopram concentrations did not affect water quality variables, bacterial composition, zooplankton and macroinvertebrate communities. In contrast to expectations based on literature, snail foot detachment was not observed while the tested concentrations overlapped with the reported effect concentrations. This is in line with the absence of indirect adverse effects of foot detachment, such as population changes that could be the result of an increased vulnerability to predation or the inability to feed or reproduce. Reported sublethal effects in the literature, as found in laboratory studies, do not appear to lead to population- or community-level impacts in a semi-field experiment within the concentration range tested in this study. The experimental outcomes suggest that environmentally relevant concentrations of citalopram might not pose a threat to water quality variables, bacterial composition, zooplankton and macroinvertebrate communities, and snail foot detachment.

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来源期刊
Environmental Pollution
Environmental Pollution 环境科学-环境科学
CiteScore
16.00
自引率
6.70%
发文量
2082
审稿时长
2.9 months
期刊介绍: Environmental Pollution is an international peer-reviewed journal that publishes high-quality research papers and review articles covering all aspects of environmental pollution and its impacts on ecosystems and human health. Subject areas include, but are not limited to: • Sources and occurrences of pollutants that are clearly defined and measured in environmental compartments, food and food-related items, and human bodies; • Interlinks between contaminant exposure and biological, ecological, and human health effects, including those of climate change; • Contaminants of emerging concerns (including but not limited to antibiotic resistant microorganisms or genes, microplastics/nanoplastics, electronic wastes, light, and noise) and/or their biological, ecological, or human health effects; • Laboratory and field studies on the remediation/mitigation of environmental pollution via new techniques and with clear links to biological, ecological, or human health effects; • Modeling of pollution processes, patterns, or trends that is of clear environmental and/or human health interest; • New techniques that measure and examine environmental occurrences, transport, behavior, and effects of pollutants within the environment or the laboratory, provided that they can be clearly used to address problems within regional or global environmental compartments.
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