Afnan M Alnajeebi, Rana Yahya, Alaa Shafie, Amal Adnan Ashour, Mohammed Fareed Felemban, Faris J Tayeb
{"title":"Highly Sensitive and Selective Detection of Hg<sup>2+</sup> ions and Antibacterial Activity Using a Schiff-base Derivative.","authors":"Afnan M Alnajeebi, Rana Yahya, Alaa Shafie, Amal Adnan Ashour, Mohammed Fareed Felemban, Faris J Tayeb","doi":"10.1007/s10895-024-04070-4","DOIUrl":null,"url":null,"abstract":"<p><p>A simple and highly effective Schiff-base fluorescent chemosensor (S1) was synthesized and characterized by <sup>1</sup>HNMR and fluorescence spectroscopy. The synthesized chemosensor was applied for the selective and sensitive detection of Hg<sup>2+</sup> ions. The chemosensor exhibited a strong 'turn-on' fluorescence response in a CH<sub>3</sub>OH/H<sub>2</sub>O (1:9, v/v) solution due to complex formation (S1-Hg<sup>2+</sup>) which block photo induce electron transfer (PET). The chemosensor showed significant sensitivity with very low detection limit of 2.0 ppb, making it suitable for trace-level Hg<sup>2+</sup> detection. Furthermore, the S1-Hg<sup>2+</sup> complex demonstrated excellent antibacterial activity against various Gram-positive and Gram-negative bacterial strains, broadening its utility beyond sensing. This dual-functional system offers significant potential in environmental and biomedical applications.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fluorescence","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s10895-024-04070-4","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
A simple and highly effective Schiff-base fluorescent chemosensor (S1) was synthesized and characterized by 1HNMR and fluorescence spectroscopy. The synthesized chemosensor was applied for the selective and sensitive detection of Hg2+ ions. The chemosensor exhibited a strong 'turn-on' fluorescence response in a CH3OH/H2O (1:9, v/v) solution due to complex formation (S1-Hg2+) which block photo induce electron transfer (PET). The chemosensor showed significant sensitivity with very low detection limit of 2.0 ppb, making it suitable for trace-level Hg2+ detection. Furthermore, the S1-Hg2+ complex demonstrated excellent antibacterial activity against various Gram-positive and Gram-negative bacterial strains, broadening its utility beyond sensing. This dual-functional system offers significant potential in environmental and biomedical applications.
期刊介绍:
Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.