Ultra-processed food intake in relation to metabolic health status in Iranian adolescents with overweight and obesity.

IF 3.9 2区医学 Q2 NUTRITION & DIETETICS Nutrition & Metabolism Pub Date : 2024-12-23 DOI:10.1186/s12986-024-00886-w

Sana Farzam, Donya Poursalehi, Saeideh Mirzaei, Ali Asadi, Masoumeh Akhlaghi, Parvane Saneei

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Abstract

Background: Many studies have explored the association between food intake and metabolic health. However, research on the association of consuming ultra-processed foods (UPFs) and metabolic health in children and adolescents remains unclear. The objective of our study was to investigate the relation between UPFs consumption and metabolic health status in Iranian adolescents with overweight/obesity.

Methods: For this cross-sectional study, we selected a sample of 203 adolescents (101 boys and 102 girls) with a mean age of 13.98 ± 1.61 who were chosen using a multistage cluster random sampling method. We collected data on their dietary patterns using a validated 147-item semi-quantitative food frequency questionnaire. Additionally, we measured anthropometric indices, blood pressure, fasting glucose, insulin, and lipid profiles. Participants were categorized to either metabolically healthy or unhealthy overweight/obesity (MHO and MUO) based on the International Diabetes Federation (IDF) and IDF/ Homeostasis Model Assessment Insulin Resistance (HOMA-IR) criteria.

Results: Our findings revealed that every 10 g/d increase in UPFs consumption was related to an elevated odds of MUO as defined by the IDF (OR = 1.14; 95%CI: 1.08-1.19) and IDF/HOMA-IR (OR = 1.14; 95%CI; 1.08-1.19) criteria, after controlling all confounders. The severity of this association varied among girls and boys and also among those with overweight and obesity according to the applied definitions. Moreover, each 10 g/d increase in daily UPFs intake was associated with increased odds of metabolic factors including hyperglycemia, hypertriglyceridemia, hypo-HDL-cholesterolemia, hypertension, and high insulin resistance levels.

Conclusion: These findings highlighted a direct association between higher UPFs consumption and MUO status among adolescents.

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伊朗超重和肥胖青少年超加工食品摄入与代谢健康状况的关系

背景：许多研究探讨了食物摄入与代谢健康之间的关系。然而，关于食用超加工食品（upf）与儿童和青少年代谢健康之间关系的研究仍不清楚。本研究的目的是调查伊朗超重/肥胖青少年UPFs摄入量与代谢健康状况之间的关系。方法：采用多阶段整群随机抽样方法，选取青少年203例，其中男生101例，女生102例，平均年龄13.98±1.61岁。我们使用一份经过验证的147项半定量食物频率问卷收集了他们饮食模式的数据。此外，我们测量了人体测量指数、血压、空腹血糖、胰岛素和脂质谱。根据国际糖尿病联合会（IDF）和IDF/稳态模型评估胰岛素抵抗（HOMA-IR）标准，参与者被分类为代谢健康或不健康的超重/肥胖（MHO和MUO）。结果：我们的研究结果显示，upf摄入量每增加10 g/d，与IDF定义的MUO几率升高相关(OR = 1.14；95%CI: 1.08-1.19)和IDF/HOMA-IR (OR = 1.14；95%可信区间;1.08-1.19)标准，在控制了所有混杂因素后。根据适用的定义，这种关联的严重程度在女孩和男孩之间以及在超重和肥胖的人群中有所不同。此外，每日UPFs摄入量每增加10克/天，代谢因素的几率就会增加，包括高血糖、高甘油三酯血症、低高密度脂蛋白胆固醇血症、高血压和高胰岛素抵抗水平。结论：这些发现强调了青少年中较高的upf消费与MUO状态之间的直接关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nutrition & Metabolism 医学-营养学

CiteScore

8.40

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Nutrition & Metabolism publishes studies with a clear focus on nutrition and metabolism with applications ranging from nutrition needs, exercise physiology, clinical and population studies, as well as the underlying mechanisms in these aspects. The areas of interest for Nutrition & Metabolism encompass studies in molecular nutrition in the context of obesity, diabetes, lipedemias, metabolic syndrome and exercise physiology. Manuscripts related to molecular, cellular and human metabolism, nutrient sensing and nutrient–gene interactions are also in interest, as are submissions that have employed new and innovative strategies like metabolomics/lipidomics or other omic-based biomarkers to predict nutritional status and metabolic diseases. Key areas we wish to encourage submissions from include: -how diet and specific nutrients interact with genes, proteins or metabolites to influence metabolic phenotypes and disease outcomes; -the role of epigenetic factors and the microbiome in the pathogenesis of metabolic diseases and their influence on metabolic responses to diet and food components; -how diet and other environmental factors affect epigenetics and microbiota; the extent to which genetic and nongenetic factors modify personal metabolic responses to diet and food compositions and the mechanisms involved; -how specific biologic networks and nutrient sensing mechanisms attribute to metabolic variability.