{"title":"A review on <i>Arum palaestinum</i>: phytochemical and biological aspects.","authors":"Ghassan Albarghouti, Baydaa' Habash","doi":"10.1080/14786419.2024.2443486","DOIUrl":null,"url":null,"abstract":"<p><p><i>Arum palaestinum</i> is a wild edible, parietal, unisexual, perennial plant that grows in various parts of the Middle East, and frequently used in traditional Arabic Palestinian herbal medicine. The present review summarises information concerning <i>Arum palaestinum</i> including background information, historical records, phytochemical components, and biological activity which represents an important tool for further research studies. <i>Arum palaestinum</i> is thought to contain a wealth of rich bioactive compounds, such as terpinoids, polyphenols, flavonoids, and alkaloids. Long-term research on these compounds has demonstrated antioxidant, antibacterial, anti-inflammatory, and anticancer activities. Its aerial parts yielded the identification of over 180 chemicals, whereas its flowering part's GC/MS study revealed the presence of twelve compounds. Its leaf extracts demonstrated toxicity against various cancer cell lines. Extracts from its flowers demonstrated potent anti-inflammatory and dose-dependent cytotoxic effects. The potential of GZ17-6.02, a promising combinatorial drug made from plant components, for clinical cancer treatment is still being investigated.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"1-18"},"PeriodicalIF":1.9000,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/14786419.2024.2443486","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Arum palaestinum is a wild edible, parietal, unisexual, perennial plant that grows in various parts of the Middle East, and frequently used in traditional Arabic Palestinian herbal medicine. The present review summarises information concerning Arum palaestinum including background information, historical records, phytochemical components, and biological activity which represents an important tool for further research studies. Arum palaestinum is thought to contain a wealth of rich bioactive compounds, such as terpinoids, polyphenols, flavonoids, and alkaloids. Long-term research on these compounds has demonstrated antioxidant, antibacterial, anti-inflammatory, and anticancer activities. Its aerial parts yielded the identification of over 180 chemicals, whereas its flowering part's GC/MS study revealed the presence of twelve compounds. Its leaf extracts demonstrated toxicity against various cancer cell lines. Extracts from its flowers demonstrated potent anti-inflammatory and dose-dependent cytotoxic effects. The potential of GZ17-6.02, a promising combinatorial drug made from plant components, for clinical cancer treatment is still being investigated.
期刊介绍：
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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