The Giant Polypore Mushroom Meripilus giganteus (Agaricomycetes): Promising Medicinal Applications (A Review).

Katarzyna Sulkowska-Ziaja, Mateusz Korczyński, Monika Trepa, Katarzyna Kala, Bozena Muszynska
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Abstract

Meripilus giganteus, commonly known as the giant polypore, is a significant basidiomycete fungus with notable ecological role and potential medicinal applications. Studies on this fungus have revealed its multifaceted bioactive properties, including antioxidant, antimicrobial, anticancer, immunosuppressive, and neuroprotective effects. Through the production of ligninolytic enzymes such as laccase, M. giganteus holds promise for bioremediation and biofuel production. Given these promising findings, further research is warranted, including genome sequencing, proteomic, and metabolomic approaches, to fully elucidate its bioactive pathways and maximize its biotechnological potential.

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巨型多孔蘑菇Meripilus giganteus(木链菌):有前景的药用应用(综述)。
巨型多孔Meripilus giganteus是一种重要的担子菌真菌,具有显著的生态作用和潜在的药用价值。对这种真菌的研究揭示了其多方面的生物活性,包括抗氧化、抗菌、抗癌、免疫抑制和神经保护作用。通过生产木质素降解酶,如漆酶,巨木霉有望用于生物修复和生物燃料生产。鉴于这些有希望的发现,需要进一步的研究,包括基因组测序,蛋白质组学和代谢组学方法,以充分阐明其生物活性途径并最大限度地发挥其生物技术潜力。
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