Vladimir L. Bondarev, Alexey A. Festa, Olga A. Storozhenko, Vladimir A. Kokorekin, Anton P. Novikov, Alexey V. Varlamov, Leonid G. Voskressensky
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引用次数: 0
Abstract
Electrolysis of o-alkynyl-N-(formyl)anilides and sodium sulfinates on graphite electrodes delivers biologically sound 3-(sulfonyl)quinol-4-ones with moderate to good yields. The reaction is carried out in an undivided cell in the presence of silver(I) oxide with potassium iodide or sodium tetrafluoroborate as the supporting electrolyte. The reaction tolerates variously substituted anilides as well as aryl and alkyl sulfinates. The transformation proceeds as a domino sequence of oxysulfonylation and cyclocondensation steps.
在石墨电极上电解邻炔基- n -（甲酰基）苯胺和亚硫酸钠可获得生物无害的3-（磺酰基）喹啉-4-酮，收率中等至较高。该反应在氧化银(I)存在的未分裂电池中进行，碘化钾或四氟硼酸钠作为支持电解质。该反应可耐受各种取代苯胺以及芳基亚硫酸盐和烷基亚硫酸盐。转化作为一个多米诺骨牌序列的氧磺化和环缩合步骤进行。
期刊介绍：
Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.
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