Nanoparticle-assisted plasmonic sensors: Recent developments in clinical applications

IF 2.6 4区生物学 Q2 BIOCHEMICAL RESEARCH METHODS Analytical biochemistry Pub Date : 2024-12-22 DOI:10.1016/j.ab.2024.115753

Duygu Çimen , Serhat Ünal , Adil Denizli

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Abstract

Nanotechnology is an important science that finds a wide range of applications from energy production to industrial production processes and biomedical applications. Nanoparti-cles, which are the most frequently preferred nanomaterials that form the basis of nanotechnolo-gy, are prepared with different composition, size, shape and surface chemistry to provide new techniques in applications in many different fields. The use of nanoparticles in the preparation of plasmonic sensors has increased the interest in plasmonic sensors such as surface plasmon resonance, electrochemical sensors, surface enhanced raman scattering and colorimetric sensors due to their increased sensing capacity on sensor surfaces. Plasmonic sensors are an important option in many different fields, such as medicine, environmental agriculture and food safety, thanks to their ability to solve a multitude of challenges. Because, plasmonic sensors are defined as sensing devices with important features such as sensitive and fast detection, no need for labels, real-time analysis, portability. In this review, the information about nanoparticles and their types and working principles of plasmonic sensors is given. Then, examples in clinical applications using different plasmonic sensors prepared with plasmonic nanoparticles are discussed in detail.

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纳米粒子辅助等离子体传感器：临床应用的最新进展。

纳米技术是一门重要的科学，有着广泛的应用，从能源生产到工业生产过程和生物医学应用。纳米粒子是最常用的纳米材料，是纳米技术的基础，它具有不同的组成、大小、形状和表面化学性质，为许多不同领域的应用提供了新的技术。纳米粒子在制备等离子体传感器中的应用增加了人们对等离子体传感器的兴趣，如表面等离子体共振、电化学传感器、表面增强拉曼散射和比色传感器，因为它们增加了传感器表面的传感能力。等离子体传感器是许多不同领域的重要选择，如医学、环境农业和食品安全，这要感谢它们解决众多挑战的能力。因为，等离子体传感器被定义为具有敏感和快速检测、不需要标签、实时分析、便携性等重要特征的传感设备。本文综述了纳米粒子及其在等离子体传感器中的种类和工作原理。然后，详细讨论了用等离子体纳米粒子制备不同等离子体传感器的临床应用实例。

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来源期刊

Analytical biochemistry 生物-分析化学

CiteScore

5.70

自引率

0.00%

发文量

283

审稿时长

44 days

期刊介绍： The journal''s title Analytical Biochemistry: Methods in the Biological Sciences declares its broad scope: methods for the basic biological sciences that include biochemistry, molecular genetics, cell biology, proteomics, immunology, bioinformatics and wherever the frontiers of research take the field. The emphasis is on methods from the strictly analytical to the more preparative that would include novel approaches to protein purification as well as improvements in cell and organ culture. The actual techniques are equally inclusive ranging from aptamers to zymology. The journal has been particularly active in: -Analytical techniques for biological molecules- Aptamer selection and utilization- Biosensors- Chromatography- Cloning, sequencing and mutagenesis- Electrochemical methods- Electrophoresis- Enzyme characterization methods- Immunological approaches- Mass spectrometry of proteins and nucleic acids- Metabolomics- Nano level techniques- Optical spectroscopy in all its forms. The journal is reluctant to include most drug and strictly clinical studies as there are more suitable publication platforms for these types of papers.