Disturbed spatial WNT activation – a potential driver of the reticularized skin phenotype in Systemic Sclerosis (SSc)

IF 11.4 1区医学 Q1 RHEUMATOLOGY Arthritis & Rheumatology Pub Date : 2024-12-25 DOI:10.1002/art.43094

Sara Chenguiti Fakhouri, Honglin Zhu, Yi-Nan Li, Moritz Ronicke, Aleix Rius Rigau, Clara Dees, Laura Konstantinidis, Ralf Schmid, Alexandru-Emil Matei, Markus Eckstein, Carol Geppert, Ingo Ludolph, Alexander Kreuter, Michael Sticherling, Carola Berking, Raymund E. Horch, Georg Schett, Jörg H.W. Distler, Christina Bergmann

引用次数: 0

Abstract

Little is known on the mechanisms necessary to maintain the physiological adult human skin integrity. This study aims to quantitatively describe anatomical changes in systemic sclerosis (SSc)-skin compared to controls and investigate the underlying mechanisms.

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来源期刊

Arthritis & Rheumatology RHEUMATOLOGY-

CiteScore

20.90

自引率

3.00%

发文量

371

期刊介绍： Arthritis & Rheumatology is the official journal of the American College of Rheumatology and focuses on the natural history, pathophysiology, treatment, and outcome of rheumatic diseases. It is a peer-reviewed publication that aims to provide the highest quality basic and clinical research in this field. The journal covers a wide range of investigative areas and also includes review articles, editorials, and educational material for researchers and clinicians. Being recognized as a leading research journal in rheumatology, Arthritis & Rheumatology serves the global community of rheumatology investigators and clinicians.

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