The blue-light receptor CRY1 serves as a switch to balance photosynthesis and plant defense

Abstract

Plant stomata open in response to blue light, allowing gas exchange and water transpiration. However, open stomata are potential entry points for pathogens. Whether plants can sense pathogens and mount defense responses upon stomatal opening and how blue-light cues are integrated to balance growth-defense trade-offs are poorly characterized. We show that the Arabidopsis blue-light photoreceptor CRYPTOCHROME 1 (CRY1) mediates various aspects of immunity, including pathogen-triggered stomatal closure as well as activation of plant immunity through a typical light-responsive protein LATE UPREGULATED IN RESPONSE TO HYALOPERONOSPORA PARASITICA (LURP1). LURP1 undergoes N-terminal palmitoylation in the presence of bacterial flagellin, prompting a change in subcellular localization from the cytoplasm to plasma membrane, where it enhances the activity of the receptor FLAGELLIN SENSING 2 (FLS2) to mediate plant defense. Collectively, these findings reveal that blue light regulates stomatal defense and highlight the dual functions of CRY1 in photosynthesis and immunity.