Amit H Alam,Candice Y Lee,Manreet K Kanwar,Yasbanoo Moayedi,Alexander M Bernhardt,Koji Takeda,Duc Thinh Pham,Christopher Salerno,Andreas Zuckermann,David D'Alessandro,Victor G Pretorius,John O Louca,Stephen Large,Dawn E Bowles,Scott C Silvestry,Nader Moazami
{"title":"Current Approaches to Optimize Donor Heart for Transplantation.","authors":"Amit H Alam,Candice Y Lee,Manreet K Kanwar,Yasbanoo Moayedi,Alexander M Bernhardt,Koji Takeda,Duc Thinh Pham,Christopher Salerno,Andreas Zuckermann,David D'Alessandro,Victor G Pretorius,John O Louca,Stephen Large,Dawn E Bowles,Scott C Silvestry,Nader Moazami","doi":"10.1016/j.healun.2024.12.001","DOIUrl":null,"url":null,"abstract":"Heart transplantation remains a critical therapy for patients with end-stage heart failure, offering incremental survival and improved quality of life. One of the key components behind the success of heart transplantation is the condition and preservation of the donor heart. In this review, we provide a comprehensive overview of ischemic reperfusion injury, risk factors associated with primary graft dysfunction, current use of various preservation solutions for organ procurement and recent advancements in donor heart procurement technologies. This State-of-the-Art review will explore factors associated with bringing the \"ideal\" donor heart to the operating room in the contemporary era.","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"63 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Heart and Lung Transplantation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.healun.2024.12.001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Heart transplantation remains a critical therapy for patients with end-stage heart failure, offering incremental survival and improved quality of life. One of the key components behind the success of heart transplantation is the condition and preservation of the donor heart. In this review, we provide a comprehensive overview of ischemic reperfusion injury, risk factors associated with primary graft dysfunction, current use of various preservation solutions for organ procurement and recent advancements in donor heart procurement technologies. This State-of-the-Art review will explore factors associated with bringing the "ideal" donor heart to the operating room in the contemporary era.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
