Journal of Heart and Lung Transplantation最新文献

{"title":"Considerations in Interpreting Pulmonary Artery Pulsatility Index and Right Ventricle -Pulmonary Arterial Coupling in Left Ventricular Assist Device Candidates.","authors":"Alina Nicoara, Mihai V Podgoreanu","doi":"10.1016/j.healun.2026.01.031","DOIUrl":"https://doi.org/10.1016/j.healun.2026.01.031","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146132088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: 10-year data on oral selexipag: long-term survival, safety, and dosing insights in pulmonary arterial hypertension from the GRIPHON study and its open-label extension - big data-small impact.","authors":"Irene M Lang","doi":"10.1016/j.healun.2026.01.030","DOIUrl":"https://doi.org/10.1016/j.healun.2026.01.030","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146132021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined heart and other organ transplants in Spain: insights from the COMBI study.","authors":"Toshihiro Nakayama, Kazunari Sasaki","doi":"10.1016/j.healun.2026.01.027","DOIUrl":"https://doi.org/10.1016/j.healun.2026.01.027","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146132058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redefining Risk Assessment with Absolute dd-cfDNA in Lung Transplantation.","authors":"Kentaro Noda, Pablo G Sanchez","doi":"10.1016/j.healun.2026.01.029","DOIUrl":"https://doi.org/10.1016/j.healun.2026.01.029","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146132074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation: Authors’ Perspective","authors":"Andrew M. Courtwright , John A. Mackintosh , Jonathan K. Alder , Christine Kim Garcia , Antoine Froidure , Erin Lowery , Don Hayes Jr. , Pali Shah , Quentin Philippot , Raphael Borie , John R. Greenland , Hannah Mannem , Mark E. Snyder , Merel Hellemons , Laurie D. Snyder , John McDyer","doi":"10.1016/j.healun.2025.10.027","DOIUrl":"10.1016/j.healun.2025.10.027","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Pages 163-167"},"PeriodicalIF":6.0,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145981999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Readers","authors":"","doi":"10.1016/S1053-2498(25)02502-1","DOIUrl":"10.1016/S1053-2498(25)02502-1","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Page A2"},"PeriodicalIF":6.0,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145982002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Considerations for Endpoints in Lung Transplant Clinical Trials: Perspective on the ISHLT Consensus Statement","authors":"John R. Greenland MD, PhD , Michael Perch MD , Kieran Halloran MD, MSc , Deborah J. Levine MD , Eric D. Morrell MD, MA , Anna Reed MBChB , Ciara M. Shaver MD, PhD , Jonathan P. Singer MD, MS , Stuart C. Sweet MD, PhD , Robin Vos MD, PhD , Shambhu Aryal MD, FCCP , Nicholas Avdimiretz MD, FRCPC , Fay Burrows Bpharm , Daniel Calabrese MD , Fiorella Calabrese MD , Silvia Campos PhD , Michael Combs MD, MS , Marc de Perrot MD, MSc, FRCSC , Göran Dellgren MD, PhD , Joshua M. Diamond MD, MS , Jamie L. Todd MD, MHS","doi":"10.1016/j.healun.2025.09.016","DOIUrl":"10.1016/j.healun.2025.09.016","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Pages 168-171"},"PeriodicalIF":6.0,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145982004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to Carnicelli et al. outcomes with Impella CP in acute myocardial infarction vs heart failure cardiogenic shock","authors":"Jacob E. Møller , Norman Mangner , Vasileios Panoulas , Christian Hassager","doi":"10.1016/j.healun.2025.09.007","DOIUrl":"10.1016/j.healun.2025.09.007","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Page 312"},"PeriodicalIF":6.0,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145981960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation","authors":"Andrew M. Courtwright MD, PhD ,&nbsp;John A. Mackintosh ,&nbsp;Jonathan K. Alder ,&nbsp;Christine Kim Garcia ,&nbsp;Antoine Froidure ,&nbsp;Erin Lowery ,&nbsp;Don Hayes Jr. ,&nbsp;Shah Pali ,&nbsp;Quentin Philippot ,&nbsp;Raphael Borie ,&nbsp;John R. Greenland ,&nbsp;Hannah Mannem ,&nbsp;Mark E. Snyder ,&nbsp;Merel Hellemons ,&nbsp;Laurie D. Snyder ,&nbsp;John McDyer","doi":"10.1016/j.healun.2025.10.028","DOIUrl":"10.1016/j.healun.2025.10.028","url":null,"abstract":"<div><div>Motivated by growing evidence that the presence of critically shortened telomeres influences interstitial lung disease (ILD) trajectories and is associated with extrapulmonary conditions relevant to lung transplant candidacy and post-transplant complications, this Consensus Statement aims to address gaps in the evaluation and management of patients with short telomere syndrome (STS). These considerations reflect the work of an international Writing Committee with expertise in STS and are grounded in current literature and expert consensus. The need for this document arises from the recognition that STS is an underdiagnosed contributor to ILD, and that its presence introduces complexities that require dedicated, multidisciplinary attention in the transplant setting.</div></div>","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Pages e83-e103"},"PeriodicalIF":6.0,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Venopulmonary extracorporeal life support: An Extracorporeal Life Support Organization registry analysis.","authors":"Luca Baldetti, Domenico Pontillo, Massimo Capoccia, Mariusz Kowalewski, Joseph E Tonna, Mikael Broman, Steven A Conrad, Justyna Swol, Anna Mara Scandroglio, J Michael Brewer, Marc O Maybauer, Roberto Lorusso","doi":"10.1016/j.healun.2025.12.024","DOIUrl":"10.1016/j.healun.2025.12.024","url":null,"abstract":"<p><strong>Background: </strong>There is a paucity of data informing on the current use, adverse events, outcomes, and prognostic drivers for patients receiving venopulmonary extracorporeal life support (VP ECLS). We aimed to provide a contemporary, large sample size study to describe the real-world outcomes of adults supported with VP ECLS across different clinical conditions.</p><p><strong>Methods: </strong>We queried the Extracorporeal Life Support Organization Registry to retrieve all adult patients who received VP ECLS as the first support modality from July 2020 to July 2024. Study population was grouped according to hospital death outcome and to the diagnosis leading to VP ECLS use. Adverse outcomes are reported according to the diagnosis leading to VP ECLS use. A time-to-event Cox regression model was applied to identify predictors of death.</p><p><strong>Results: </strong>A total of 838 patients [32.3% females; age 8 (46, 67) years] were included. Patients were treated for heart failure/cardiogenic shock (HF/CS) in 54.4%, for acute respiratory failure/acute respiratory distress syndrome (ARF/ARDS) in 26.6%, for post-cardiotomy shock in 6.7%, for acute coronary syndrome/ischemic heart disease in 5.3%, for valvular heart disease/complications of intracardiac devices in 4.2%, and for pulmonary embolism in 2.9%. Most common adverse events included continuous renal replacement therapy (CRRT) use or acute kidney injury (37.4%), infections (35.4%), cardiac arrhythmias (13.5%), surgical site bleeding (12.1%), gastrointestinal (GI) bleeding (6.1%). Complications were more common in non-survivors and patterns of complications differed among diagnosis groups. The Kaplan-Meier estimated 60-day survival was 49.3 (45.3, 53.1)%. Age (HR_adj 1.15 for 5 years increase; 95%CI 1.11, 1.20; p < 0.001), female sex (HR_adj 1.40; 95%CI 1.12, 1.76; p = 0.003), body mass index (HR_adj 1.02 for 3 kg/m² increase; 95%CI 1.01, 1.04; p < 0.018), CRRT use prior VP ECLS cannulation (HR_adj 1.44; 95%CI 1.11, 1.86; p < 0.006) were independent predictors of death.</p><p><strong>Conclusions: </strong>In this large Extracorporeal Life Support Organization registry analysis, VP ECLS was chiefly used for HF/CS and ARF/ARDS. Hospital outcomes, complications, and survival differed according to the diagnosis leading to VP ECLS use. Younger age, male sex, lower BMI, and no CRRT use prior to VP ECLS cannulation confer a lower risk of death and provide targets for future research and potential domains for clinical improvement.</p>","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}