Rhodium(III)‐Catalyzed [4+2] Annulation of N‐Hydroxyoximes with Maleate Esters/2‐Chloroacrylates: Synthesis of Isoquinoline‐3,4‐Dicarboxylates and Isoquinoline‐3‐Carboxylates
He Li , Tao Chen , Zhiwei Wang , Yuxin Li , Baoheng Wu , Ning Xu , Ye Lu , Xinxin Jin , Jiaqi Yu , Jinglin Liu , Ming Bao
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引用次数: 0
Abstract
A novel Rh(III)‐catalyzed [4+2] annulation of N‐hydroxyoximes with maleate esters/2‐chloroacrylates is disclosed, in which diverse isoquinoline skeleton compounds were generated in moderate to excellent yields. The protocol exhibits a good compatibility of functional groups and wide scope of substrates without using any external metal oxidants. Gram‐scale and derivatization reactions were performed to show the potential utility of this transformation.
期刊介绍：
The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies.
The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry:
Liebigs Annalen
Bulletin des Sociétés Chimiques Belges
Bulletin de la Société Chimique de France
Gazzetta Chimica Italiana
Recueil des Travaux Chimiques des Pays-Bas
Anales de Química
Chimika Chronika
Revista Portuguesa de Química
ACH—Models in Chemistry
Polish Journal of Chemistry.
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