Analysis strategy of contamination source using chemical fingerprint information based on GC-HRMS: a case study of landfill leachate

Abstract

With the increasing prevalence of emerging contaminants (ECs) in the environment, gaining a deeper understanding of the chemical information pertaining to the contamination source is a crucial step toward effective prevention and control of these ECs. This study presents a novel strategy for analyzing the chemical information of contamination sources using gas chromatography-high resolution mass spectrometry (GC-HRMS) and demonstrates it on landfill leachate, a common and representative environmental contamination source. Initially, a non-targeted screening approach using HRMS was used to characterize a total of 5344 organic compounds with identification confidence levels 1 and 2 in 14 landfill leachate samples. Leveraging this as a base data set, the similarity analysis was first performed, and the classification fingerprints exhibited a pronounced level of similarity. Second, 169 characteristic marker contaminants with important and significant differences were identified in the 3 groups of landfill leachate with different solid waste compositions (mostly kitchen waste, mostly plastic & daily chemical product waste, and proportion average) by difference analysis. Finally, 101 hazardous chemicals (HCs) were screened in the data set. The results demonstrated that a class of contamination source exhibited certain common characteristics, while different groups of samples had their own distinct contamination signatures. This work offers a unique perspective on the interpretation of chemical information from contamination sources, aiming to provide a valuable reference for environmental pollution management.