Uncommon Nasal Mass Presentation: A Radiological Case Series.

IF 3 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Journal of Personalized Medicine Pub Date : 2024-12-09 DOI:10.3390/jpm14121145
Antonio Lo Casto, Francesco Lorusso, Ettore Palizzolo, Federico Sireci, Francesco Dispenza, Manfredi De Angelis, Angelo Immordino, Salvatore Gallina, Francesco Bencivinni
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Abstract

Background: Nasal and paranasal sinus masses can arise from a wide range of conditions, both benign and malignant, as well as congenital or acquired. Diagnosing these masses is often challenging, requiring a combination of nasal endoscopy, imaging studies, and histopathological analysis. Initial imaging frequently involves computed tomography or cone beam computed tomography (CBCT) to evaluate the bony anatomy of the nasal cavity and surrounding sinuses, while magnetic resonance imaging (MRI) is typically used for detailed assessment of soft tissues and to aid in differential diagnosis when the findings are inconclusive. Methods: This review examines nasal masses evaluated using CT, CBCT, and MRI, highlighting key imaging features that may assist in differential diagnosis. Results: For non-neoplastic lesions, examples include conditions such as rhinoliths, inverted mesiodens, and septal mucoceles. Benign and borderline tumors discussed encompass lobular capillary hemangioma, inverted papilloma, septal osteoma, chondromesenchymal hamartoma, hemangioma, hemangiopericytoma, antrochoanal polyp, sinonasal angiofibroma, ossifying fibroma, and lipoma. Malignant tumors addressed in this review include adenocarcinoma, esthesioneuroblastoma, non-Hodgkin lymphoma, melanoma, and sarcoma. Conclusions: Diagnosing nasal lesions represent a significant challenge for otolaryngologists. Imaging characteristics of nasal masses play a crucial role in narrowing down differential diagnoses before surgery. However, nasal endoscopy combined with biopsy remains the definitive diagnostic approach.

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罕见的鼻肿块表现:一个放射学病例系列。
背景:鼻和副鼻窦肿块可由多种情况引起,包括良性和恶性,以及先天性或后天性。诊断这些肿块通常具有挑战性,需要结合鼻内窥镜检查、影像学检查和组织病理学分析。初始成像通常包括计算机断层扫描或锥形束计算机断层扫描(CBCT)来评估鼻腔和周围鼻窦的骨骼解剖,而磁共振成像(MRI)通常用于详细评估软组织,并在发现不确定时帮助鉴别诊断。方法:本文回顾了使用CT、CBCT和MRI评估的鼻肿块,突出了可能有助于鉴别诊断的关键影像学特征。结果:对于非肿瘤性病变,例子包括鼻石,中隔内翻和中隔粘液囊肿。讨论的良性和交界性肿瘤包括小叶毛细血管瘤、内翻性乳头状瘤、中隔骨瘤、软骨间充质错构瘤、血管瘤、血管外皮细胞瘤、鼻窦息肉、鼻血管纤维瘤、骨化纤维瘤和脂肪瘤。恶性肿瘤包括腺癌、神经母细胞瘤、非霍奇金淋巴瘤、黑色素瘤和肉瘤。结论:诊断鼻病变是耳鼻喉科医师面临的一个重大挑战。鼻肿块的影像学特征对术前鉴别诊断具有重要意义。然而,鼻内窥镜联合活检仍然是明确的诊断方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Personalized Medicine
Journal of Personalized Medicine Medicine-Medicine (miscellaneous)
CiteScore
4.10
自引率
0.00%
发文量
1878
审稿时长
11 weeks
期刊介绍: Journal of Personalized Medicine (JPM; ISSN 2075-4426) is an international, open access journal aimed at bringing all aspects of personalized medicine to one platform. JPM publishes cutting edge, innovative preclinical and translational scientific research and technologies related to personalized medicine (e.g., pharmacogenomics/proteomics, systems biology). JPM recognizes that personalized medicine—the assessment of genetic, environmental and host factors that cause variability of individuals—is a challenging, transdisciplinary topic that requires discussions from a range of experts. For a comprehensive perspective of personalized medicine, JPM aims to integrate expertise from the molecular and translational sciences, therapeutics and diagnostics, as well as discussions of regulatory, social, ethical and policy aspects. We provide a forum to bring together academic and clinical researchers, biotechnology, diagnostic and pharmaceutical companies, health professionals, regulatory and ethical experts, and government and regulatory authorities.
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