Phytochemical analysis of bioactive compounds in Pisolithus albus (Cooke & Massee) Priest mushrooms: potential applications in medicine and biotechnology.

IF 1.6 3区 化学 Q3 CHEMISTRY, APPLIED Natural Product Research Pub Date : 2024-12-26 DOI:10.1080/14786419.2024.2445203
Wassima Lakhdari, Mustapha Mounir Bouhenna, Bendif Hamdi, Ibtissem Benyahia, Hakim Bachir, Hamida Hammi, Djawahir Mouhoubi, Boussebaa Walid, Maurizio Bruno, Natale Badalamenti, Abderrahmene Dehliz
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Abstract

Mushrooms have proven to be a valuable source of diverse bioactive compounds that can hold substantial potential for preventing and managing various diseases. This research focused on examining the numerous bioactive compounds found in Pisolithus albus (P. albus) (Cooke & Massee) Priest mushrooms, particularly those obtained from ethyl acetate and dichloromethane extracts. Polyphenols, flavonoids, tannins, and alkaloids were also evaluated by chemical analysis. Furthermore, the bioactive compounds of extracts were identified using thin-layer chromatography (TLC), gas chromatography-mass spectrometry (GC-MS), and Liquid Chromatography Mass Spectrometry (LC-MS). Evident diversity in the phytochemical composition was noted between the ethyl acetate (EtOAc) and dichloromethane (DCM) extracts, identifying through spectrometric methods interesting bioactive compounds that exhibit potential utility across medicinal and agricultural domains, including their application as herbicides. This study not only shed light on the bioactive constituents within the two types of extracts but also underscored the advantageous compounds inherent in P. albus mushrooms.

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白菇(Pisolithus albus (Cooke & Massee) Priest)中生物活性化合物的植物化学分析:在医学和生物技术方面的潜在应用。
蘑菇已被证明是多种生物活性化合物的宝贵来源,具有预防和管理各种疾病的巨大潜力。这项研究的重点是检测在白菇(P. albus) (Cooke & Massee) Priest蘑菇中发现的许多生物活性化合物,特别是那些从乙酸乙酯和二氯甲烷提取物中获得的化合物。多酚、类黄酮、单宁和生物碱也通过化学分析进行了评价。此外,采用薄层色谱(TLC)、气相色谱-质谱(GC-MS)和液相色谱-质谱(LC-MS)对提取物的生物活性成分进行了鉴定。在乙酸乙酯(EtOAc)和二氯甲烷(DCM)提取物之间发现了明显的植物化学成分差异,通过光谱方法鉴定出在药用和农业领域具有潜在用途的有趣的生物活性化合物,包括它们作为除草剂的应用。本研究不仅揭示了两种提取物的生物活性成分,而且强调了白孢蘑菇固有的有利化合物。
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来源期刊
Natural Product Research
Natural Product Research 化学-医药化学
CiteScore
5.10
自引率
9.10%
发文量
605
审稿时长
2.1 months
期刊介绍: The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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