[Analysis of treatment outcomes of extremely preterm infants in a real-world single center].

Lei Xia, Jia-Wen Zhao, Hui-Juan Wang, Qing Qiao, Tian-Bo Wu, Hui-Jie Wu
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Abstract

Objectives: To study the treatment outcomes of extremely preterm infants.

Methods: A retrospective analysis was performed for the clinical data of extremely preterm infants who were admitted to the neonatal intensive care unit of the Third Affiliated Hospital of Zhengzhou University from January 2016 to December 2022. The infants were divided into a non-in-hospital death group and a survival group. SPSS 29.0 was used for data analysis.

Results: A total of 422 extremely preterm infants were included, of which 155 were in the non-in-hospital death group and 267 in the survival group. The gestational age, birth weight, cesarean section rate, and proportion of mothers with premature rupture of membranes >18 hours in the non-in-hospital death group were all lower than those in the survival group (P<0.05). In contrast, the proportions of Apgar score ≤3 at 1 minute, intubation, neonatal respiratory distress syndrome, early-onset sepsis, periventricular-intraventricular hemorrhage (grades III-IV), and pneumorrhagia were higher in the non-in-hospital death group compared to the survival group (P<0.05).

Conclusions: Low gestational age, low birth weight, the history of birth asphyxia, severe intracranial hemorrhage, and pneumorrhagia may be the main causes of non-in-hospital death in extremely preterm infants, and therefore, perinatal health care should be enhanced to reduce the onset of asphyxia and severe diseases.

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[现实世界单中心极早产儿治疗结果分析]。
目的:探讨极早产儿的治疗效果。方法:回顾性分析2016年1月至2022年12月郑州大学第三附属医院新生儿重症监护病房收治的极早产儿临床资料。这些婴儿被分为非住院死亡组和存活组。采用SPSS 29.0进行数据分析。结果:共纳入极早产儿422例,其中非院内死亡组155例,生存组267例。非院内死亡组的胎龄、出生体重、剖宫产率、胎膜早破比例(bbb18 h)均低于存活组(ppp)。低胎龄、低出生体重、出生窒息史、严重颅内出血、肺出血可能是极早产儿非院内死亡的主要原因,因此,应加强围产期保健,减少窒息和严重疾病的发生。
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来源期刊
中国当代儿科杂志
中国当代儿科杂志 Medicine-Pediatrics, Perinatology and Child Health
CiteScore
1.50
自引率
0.00%
发文量
5006
期刊介绍: The Chinese Journal of Contemporary Pediatrics (CJCP) is a peer-reviewed open access periodical in the field of pediatrics that is sponsored by the Central South University/Xiangya Hospital of Central South University and under the auspices of the Ministry of Education of China. It is cited as a source in the scientific and technological papers of Chinese journals, the Chinese Science Citation Database (CSCD), and is one of the core Chinese periodicals in the Peking University Library. CJCP has been indexed by MEDLINE/PubMed/PMC of the American National Library, American Chemical Abstracts (CA), Holland Medical Abstracts (EM), Western Pacific Region Index Medicus (WPRIM), Scopus and EBSCO. It is a monthly periodical published on the 15th of every month, and is distributed both at home and overseas. The Chinese series publication number is CN 43-1301/R;ISSN 1008-8830. The tenet of CJCP is to “reflect the latest advances and be open to the world”. The periodical reports the most recent advances in the contemporary pediatric field. The majority of the readership is pediatric doctors and researchers.
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