Building bridges from research outcomes to clinical practice decisions.

David W Chambers, Carlos Flores-Mir
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Abstract

Practitioners may face difficulties implementing research results into practice. Seven examples of common knowledge translation barriers for clinicians are presented, and suggestions are offered for building effective communication bridges. Changes in how research results are reported and interpreted across different practice contexts can improve orthodontic care. These include (a) attention to the expected benefit that includes estimates of both likely clinical value and probability of occurrence, (b) cost considerations, (c) generalizability across contexts that require interpretation adjustments, (d) measures of effect size in addition to measures of statistical significance, (e) determination of the largest relative sources of variance in the reported results, (f) estimating probabilities that lead to practice actions, and (g) conversion of research descriptions to values that impact practice decisions. Examples of improved communication relevant to clinicians are provided that can be used to build stronger bridges between orthodontic research and practice. Although advances in orthodontic research rigor have been noted, journal articles would benefit from more clinician-friendly descriptions of results and their impact.

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建立从研究成果到临床实践决策的桥梁。
从业者在将研究成果应用到实践中可能会面临困难。本文列举了临床医生常见知识翻译障碍的七个例子,并提出了建立有效沟通桥梁的建议。在不同的实践背景下如何报告和解释研究结果的变化可以改善正畸护理。这些包括(a)对预期收益的关注,包括对可能的临床价值和发生概率的估计,(b)成本考虑,(c)需要解释调整的情况下的概括性,(d)除统计显著性测量外的效应大小测量,(e)确定报告结果中最大的相对方差来源,(f)估计导致实践行动的概率,(g)将研究描述转化为影响实践决策的价值。提供了与临床医生有关的改进沟通的例子,可用于在正畸研究和实践之间建立更牢固的桥梁。虽然在正畸研究的严谨性的进步已经被注意到,期刊文章将受益于更多的临床友好的结果及其影响的描述。
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