Concentrated autologous bone marrow injection in the surgical treatment of scaphoid non-union.

Pierre Maincourt, Christophe Andro, Arnaud Perchoc, Thomas Daoulas, Weiguo Hu, Anne Perruisseau-Carrier
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Abstract

New surgical techniques for the treatment of scaphoid non-union, developed in the last two decades, now enable a healing rate of 80-90%. However, no consensus exists for the surgical treatment of non-union. On the other hand, regenerative medicine techniques have enriched the therapeutic armamentarium for non-union, especially in the lower limbs, with the use of autologous concentrated bone marrow injection using autologous osteogenic precursors to create a favorable microenvironment for bone healing. This technique has the advantages of being inexpensive, easily accessible and applicable in scaphoid non-union as a biological adjuvant to surgery, to improve both healing times and rates. We report 6-month clinical results for the first patient receiving autologous concentrated bone marrow injection associated to scaphoid screw fixation in our center.

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自体骨髓浓缩注射在舟状骨不连手术治疗中的应用。
在过去二十年中发展起来的治疗舟状骨不连的新手术技术,现在使治愈率达到80-90%。然而,对于骨不连的手术治疗尚无共识。另一方面,再生医学技术丰富了骨不连的治疗手段,尤其是下肢骨不连,利用自体成骨前体进行自体浓缩骨髓注射,为骨愈合创造了有利的微环境。该技术的优点是价格低廉,易于获得,可作为手术的生物辅助,用于舟状骨不愈合,以提高愈合时间和愈合率。我们报告了本中心首位接受自体浓缩骨髓注射与舟状骨螺钉固定相关的患者6个月的临床结果。
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