Sodium-dependent glucose transporter 2 inhibitors: Transforming diabetic cardiomyopathy management.

IF 1.9 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS World Journal of Cardiology Pub Date : 2024-12-26 DOI:10.4330/wjc.v16.i12.781
Chun-Han Cheng, Wen-Rui Hao, Tzu-Hurng Cheng
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Abstract

This article addresses the substantial findings of a study on sodium-dependent glucose transporter 2 inhibitors (SGLT2is) and their effects on myocardial function in patients with type 2 diabetes and asymptomatic heart failure. The editorial explores the broader implications of the study findings for clinical practice, thus highlighting the pivotal role of SGLT2is in improving cardiac function, reducing oxidative stress, and attenuating inflammation. It emphasizes the importance of early intervention with SGLT2is in preventing the progression of diabetic cardiomyopathy; hence, these inhibitors have the potential to transform the management of asymptomatic heart failure in patients with diabetes.

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钠依赖性葡萄糖转运蛋白2抑制剂:改变糖尿病性心肌病的管理。
本文阐述了钠依赖性葡萄糖转运蛋白2抑制剂(SGLT2is)及其对2型糖尿病合并无症状心力衰竭患者心肌功能影响的研究结果。这篇社论探讨了该研究结果对临床实践的更广泛意义,从而强调了SGLT2is在改善心功能、减少氧化应激和减轻炎症方面的关键作用。它强调了早期干预SGLT2is在预防糖尿病性心肌病进展中的重要性;因此,这些抑制剂有可能改变糖尿病患者无症状心力衰竭的治疗。
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来源期刊
World Journal of Cardiology
World Journal of Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.30
自引率
5.30%
发文量
54
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