Exploring Patient Perspectives: A Structured Interview Study on Deep Brain Stimulation as a Novel Treatment Approach for Mild Cognitive Impairment.

Q1 Neuroscience AJOB Neuroscience Pub Date : 2024-12-31 DOI:10.1080/21507740.2024.2438033

Pooja Venkatesh, Bradley Lega, Michael Rubin

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Abstract

Introduction: Limited treatments for Mild Cognitive Impairment (MCI) highlight the need to explore innovations including Deep Brain Stimulation (DBS), with patient perspectives key to ethical protocol development.

Methods: Seven MCI patients and four care partners were interviewed (Feb 2023-Jan 2024) about daily MCI challenges, desired treatment outcomes, and views on DBS. Thematic analysis following COREQ guidelines identified key themes.

Results: DBS was a novel concept for all (7/7), and most expressed interest (6/7) despite concerns about invasiveness (6/7) and preference to exhaust medications first (4/7). Care partners (4/4) shared concerns about invasiveness and emphasized proven efficacy. Key deciding factors included the involved procedural risk (6/7), desired significant outcomes (6/7), and prior testing for MCI (7/7). Most participants (6/7) were hesitant to be the first to try DBS, while one was willing.

Conclusion: Patient and care partner insights on DBS for MCI are crucial for balancing innovation with ethical, patient-centered research.

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探索患者观点：深部脑刺激作为轻度认知障碍新治疗方法的结构化访谈研究。

简介：轻度认知障碍（MCI）的有限治疗突出了探索创新的必要性，包括深部脑刺激（DBS），患者的观点是伦理方案制定的关键。方法：在2023年2月至2024年1月期间，对7名MCI患者和4名护理伙伴进行了访谈，内容包括日常MCI挑战、期望的治疗结果以及对DBS的看法。根据COREQ指导方针进行主题分析，确定了关键主题。结果：DBS对所有人来说都是一个新颖的概念（7/7），尽管担心侵入性（6/7）和首选先用尽药物（4/7），但大多数人表示感兴趣（6/7）。护理合作伙伴（4/4）分享了对侵入性的担忧，并强调了已证实的疗效。关键决定因素包括所涉及的手术风险（6/7）、期望的显著结果（6/7）和先前的MCI检测（7/7）。大多数参与者（6/7）对第一个尝试DBS犹豫不决，而一个人愿意。结论：患者和护理伙伴对DBS治疗MCI的见解对于平衡创新与道德、以患者为中心的研究至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

AJOB Neuroscience Neuroscience-Neuroscience (all)

CiteScore

12.20

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0.00%

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