Developing and Comparing Four Families of Bayesian Network Autocorrelation Models for Binary Outcomes: Estimating Peer Effects Involving Adoption of Medical Technologies

IF 1.3 3区 生物学 Q4 MATHEMATICAL & COMPUTATIONAL BIOLOGY Biometrical Journal Pub Date : 2024-12-30 DOI:10.1002/bimj.70030
Guanqing Chen, A. James O'Malley
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Abstract

Despite the extensive use of network autocorrelation models in social network analysis, network autocorrelation models for binary dependent variables have received surprisingly scant attention. In this paper, we develop four network autocorrelation models for a binary random variable defined by whether the peer effect (also termed social influence or contagion) acts on latent continuous outcomes leading to an indirect effect under a normal or a logistic distribution or on the probability of the observed outcome itself under a probit or a logit link function defining a direct effect to account for interdependence between outcomes. For all models, we use a Bayesian approach for model estimation under a uniform prior on a transformed peer effect parameter ( ρ $\rho$ ) designed to enhance model computation and compare results to those under the uniform prior for ρ $\rho$ . We use simulation to assess the performance of Bayesian point and interval estimators for each of the four models when the model that generated the data is used for estimation (precision assessment) and when each of the other three models instead generated the data (robustness assessment). We construct a United States New England region patient-sharing hospital network and apply the four network autocorrelation models to study the adoption of robotic surgery, a new medical technology, among hospitals using a cohort of United States Medicare beneficiaries in 2016 and 2017. Finally, we develop a deviance information criterion for each of the four models to compare their fit to the observed data and use posterior predictive p-values to assess the models' ability to recover specified features of the data. The results find that although the indirect peer effect of the propensity of peer hospital adoption on that of the focal hospital is positive under both latent response autocorrelation models, the direct peer effect of the peer hospital's probability of adopting robotic surgery on the probability of the focal hospital adopting robotic surgery decreases under both mean autocorrelation data models. However, neither of these associations is statistically significant.

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发展和比较四类贝叶斯网络自相关模型的二元结果:估计涉及医疗技术采用的同伴效应。
尽管网络自相关模型在社会网络分析中得到了广泛的应用,但二元因变量的网络自相关模型却很少受到关注。在本文中,我们为一个二元随机变量开发了四个网络自相关模型,其定义是同伴效应(也称为社会影响或传染)是否作用于潜在的连续结果,导致正态分布或逻辑分布下的间接效应,或作用于probit或logit链接函数下观察到的结果本身的概率,定义了直接效应,以解释结果之间的相互依赖性。对于所有模型,我们使用贝叶斯方法对转换的对等效应参数(ρ $\rho$)进行均匀先验下的模型估计,旨在增强模型计算并将结果与ρ $\rho$均匀先验下的结果进行比较。当生成数据的模型用于估计(精度评估)以及其他三个模型中的每一个模型生成数据(鲁棒性评估)时,我们使用模拟来评估贝叶斯点和区间估计器对四个模型中的每一个模型的性能。我们构建了一个美国新英格兰地区的患者共享医院网络,并应用四个网络自相关模型研究了2016年和2017年美国医疗保险受益人队列中医院对机器人手术这一新型医疗技术的采用情况。最后,我们为每个模型开发了一个偏差信息标准,以比较它们与观测数据的拟合,并使用后验预测p值来评估模型恢复数据特定特征的能力。结果发现,在两种潜在反应自相关模型下,同行医院采用机器人手术的概率对焦点医院采用机器人手术的概率的间接对等效应均为正,而在两种平均自相关数据模型下,同行医院采用机器人手术的概率对焦点医院采用机器人手术的概率的直接对等效应均减小。然而,这两种关联在统计上都不显著。
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来源期刊
Biometrical Journal
Biometrical Journal 生物-数学与计算生物学
CiteScore
3.20
自引率
5.90%
发文量
119
审稿时长
6-12 weeks
期刊介绍: Biometrical Journal publishes papers on statistical methods and their applications in life sciences including medicine, environmental sciences and agriculture. Methodological developments should be motivated by an interesting and relevant problem from these areas. Ideally the manuscript should include a description of the problem and a section detailing the application of the new methodology to the problem. Case studies, review articles and letters to the editors are also welcome. Papers containing only extensive mathematical theory are not suitable for publication in Biometrical Journal.
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