Versatile Synthesis of Linalool-Derived Compounds via Catalytic Epoxidation and Ring Opening

Abstract

This study focuses on the selective epoxidation of linalool to produce linalool epoxide, and novel linalool-derived compounds from this epoxide. A robust and non-noble cobalt catalyst was employed to achieve high yields of linalool epoxide under mild reaction conditions. The catalytic system displayed remarkable efficiency and reusability, providing a platform for exploring different feedstock, including rosewood oil, to demonstrate its versatility in raw feedstock valorization. Further functionalization of linalool-derived molecules was achieved through regioselective ring-opening reactions, yielding novel ethers with potential applications in the fine chemical industry. In summary, this study presents a comprehensive approach to the sustainable synthesis of linalool-derived compounds, displaying the versatility of the catalytic system and providing a basis for the development of fine organic compounds with potential industrial applications.