Jingjing Liu, Fengjun Shi, Sisi Ma, Jing Sun, Sen Liu, Wei Ye
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引用次数: 0
Abstract
Bacterial infection of an implant can cause implant failure and lead to complications. Magnesium and its alloys have been selected as implant materials, since they are biodegradable and possess suitable elastic moduli. However, the rapid rate of degradation of magnesium and its alloys in the body, as well as attachment of bacterial cells on their surfaces, limits their application as implants. Therefore, this paper reports a superhydrophilic magnesium/gallium-layered double hydroxides (SH/Mg-Ga LDHs) coating. The SH/Mg-Ga LDHs coating exhibited excellent superhydrophilic properties and prevented bacterial attachment on the surface of magnesium alloy. Furthermore, the coating demonstrated outstanding antibacterial performance, with inhibition rates exceeding 99% against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). Additionally, the coating reduced the corrosion current density of the magnesium alloy from 7.49 × 10–6 to 1.67 × 10–7 A/cm2, and increased the corrosion potential from − 1.55 V/SCE to − 0.35 V/SCE, thereby significantly improving the corrosion resistance of the magnesium alloy. The number of platelets adhering to the coating was nearly zero, and the thrombosis index increased from 92 to 96%, effectively preventing thrombus formation. Therefore, the Mg-Ga LDHs coating provided a feasible solution to improve the properties of magnesium alloy implant materials and promote the application of magnesium alloys.
期刊介绍：
The objective of the Journal of Nanoparticle Research is to disseminate knowledge of the physical, chemical and biological phenomena and processes in structures that have at least one lengthscale ranging from molecular to approximately 100 nm (or submicron in some situations), and exhibit improved and novel properties that are a direct result of their small size.
Nanoparticle research is a key component of nanoscience, nanoengineering and nanotechnology.
The focus of the Journal is on the specific concepts, properties, phenomena, and processes related to particles, tubes, layers, macromolecules, clusters and other finite structures of the nanoscale size range. Synthesis, assembly, transport, reactivity, and stability of such structures are considered. Development of in-situ and ex-situ instrumentation for characterization of nanoparticles and their interfaces should be based on new principles for probing properties and phenomena not well understood at the nanometer scale. Modeling and simulation may include atom-based quantum mechanics; molecular dynamics; single-particle, multi-body and continuum based models; fractals; other methods suitable for modeling particle synthesis, assembling and interaction processes. Realization and application of systems, structures and devices with novel functions obtained via precursor nanoparticles is emphasized. Approaches may include gas-, liquid-, solid-, and vacuum-based processes, size reduction, chemical- and bio-self assembly. Contributions include utilization of nanoparticle systems for enhancing a phenomenon or process and particle assembling into hierarchical structures, as well as formulation and the administration of drugs. Synergistic approaches originating from different disciplines and technologies, and interaction between the research providers and users in this field, are encouraged.
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