Recent advances in the development of enantiopure BODIPYs and some related enantiomeric compounds

Abstract

During the process of developing smart chiroptical luminophores, small chiral organic dyes have emerged as candidates of utmost importance. In this regard, the chiral variants of boron dipyrromethene (BODIPY) serve as suitable molecules owing to their excellent photophysical properties such as high fluorescence quantum yields, narrow emission bandwidths with high peak intensities, high photo and chemical stability, and higher molar extinction coefficients. Thus, the last decade observed an influx of research from various research groups for the induction of chirality in originally achiral BODIPY. Among these, the generation of chiral centers at various positions in BODIPY favored the synthetic accessibility towards this particular chiral pool, which in turn is found to be applicable in various areas like photodynamic therapy, bio-imaging, dye-sensitized solar cells, optoelectronics, fluorescent indicators, dye lasers, and chiral sensing. This review summarizes these various aspects of creating stereogenic centers at various positions, like α, β, meso, or at boron, in BODIPYs.