Nanotechnology and nanobots unleashed: pioneering a new era in gynecological cancer management - a comprehensive review.

IF 2.7 4区 医学 Q3 ONCOLOGY Cancer Chemotherapy and Pharmacology Pub Date : 2025-01-04 DOI:10.1007/s00280-024-04747-4
Naina Kumar, Mishu Mangla
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Abstract

Introduction: Gynecological cancers, such as ovarian, cervical, and endometrial malignancies, are notoriously challenging due to their intricate biology and the critical need for precise diagnostic and therapeutic approaches. In recent years, groundbreaking advances in nanotechnology and nanobots have emerged as game-changers in this arena, offering the promise of a new paradigm in cancer management. This comprehensive review delves into the revolutionary potential of these technologies, showcasing their ability to transform the landscape of gynecological oncology.

Methodology: A systematic literature search spanning from March 2005 to August 2024 was conducted using major databases such as PubMed, Google Scholar, and Scopus. Keywords included "nanotechnology," "nanobots," "gynecological cancers," "ovarian cancer," "cervical cancer," and "endometrial cancer." Relevant articles published in English were selected based on their focus on nanotechnology and nanobots in the diagnosis, treatment, and management of gynecological cancers. The findings were synthesized to present a coherent overview of how nanotechnology and nanobots are reshaping gynecological cancer management. The review highlights key innovations, current applications, and future directions for research and clinical implementation.

Conclusion: The integration of nanotechnology and nanobots in gynecological cancer management represents a groundbreaking shift in the field. Recent advancements in nanoscale materials and robotic technology offer unprecedented opportunities for precision diagnosis, targeted drug delivery, and innovative therapeutic approaches. Despite promising developments, challenges such as biocompatibility, safety, and regulatory issues remain. Continued research and clinical trials are essential to overcome these hurdles and fully realize the potential of nanotechnology and nanobots.

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纳米技术和纳米机器人释放:开创妇科癌症管理的新时代-全面回顾。
妇科癌症,如卵巢癌、宫颈癌和子宫内膜恶性肿瘤,由于其复杂的生物学和对精确诊断和治疗方法的迫切需要,是众所周知的具有挑战性的。近年来,纳米技术和纳米机器人的突破性进展已经成为这一领域的游戏规则改变者,为癌症管理提供了新的范例。这篇全面的综述深入研究了这些技术的革命性潜力,展示了它们改变妇科肿瘤学景观的能力。方法:利用PubMed、b谷歌Scholar、Scopus等主要数据库对2005年3月至2024年8月的文献进行系统检索。关键词包括“纳米技术”、“纳米机器人”、“妇科癌症”、“卵巢癌”、“宫颈癌”和“子宫内膜癌”。根据纳米技术和纳米机器人在妇科癌症的诊断、治疗和管理方面的重点,选择了相关的英文论文。综合这些发现,对纳米技术和纳米机器人如何重塑妇科癌症管理进行了连贯的概述。这篇综述强调了关键的创新、当前的应用以及未来的研究和临床实施方向。结论:纳米技术和纳米机器人在妇科肿瘤治疗中的应用代表了该领域的突破性转变。纳米材料和机器人技术的最新进展为精确诊断、靶向给药和创新治疗方法提供了前所未有的机会。尽管前景看好,但生物相容性、安全性和监管问题等挑战依然存在。持续的研究和临床试验对于克服这些障碍和充分实现纳米技术和纳米机器人的潜力至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.10
自引率
3.30%
发文量
116
审稿时长
2.5 months
期刊介绍: Addressing a wide range of pharmacologic and oncologic concerns on both experimental and clinical levels, Cancer Chemotherapy and Pharmacology is an eminent journal in the field. The primary focus in this rapid publication medium is on new anticancer agents, their experimental screening, preclinical toxicology and pharmacology, single and combined drug administration modalities, and clinical phase I, II and III trials. It is essential reading for pharmacologists and oncologists giving results recorded in the following areas: clinical toxicology, pharmacokinetics, pharmacodynamics, drug interactions, and indications for chemotherapy in cancer treatment strategy.
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