Neoself-antigen presentation in SLE: Mordred’s coronation in Arthur’s absence

IF 25.9 1区 生物学 Q1 CELL BIOLOGY Cell Research Pub Date : 2025-01-06 DOI:10.1038/s41422-024-01052-w
Mehrdad Pazhouhandeh, Hongjian Sun, Di Yu
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SLE的新自身抗原表现：亚瑟王缺席时莫德雷德的加冕
最近，Hisashi Arase博士领导的一项研究发表在《细胞》杂志上，报道了系统性红斑狼疮自身耐受性破坏的新机制，即自身反应性T细胞识别新自身抗原。新自身抗原，包括一系列自身分子，被证明是通过非规范机制在不变链蛋白下调后出现在主要组织相容性复合体II类上。
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来源期刊
Cell Research
Cell Research 生物-细胞生物学
CiteScore
53.90
自引率
0.70%
发文量
2420
审稿时长
2.3 months
期刊介绍： Cell Research (CR) is an international journal published by Springer Nature in partnership with the Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CAS). It focuses on publishing original research articles and reviews in various areas of life sciences, particularly those related to molecular and cell biology. The journal covers a broad range of topics including cell growth, differentiation, and apoptosis; signal transduction; stem cell biology and development; chromatin, epigenetics, and transcription; RNA biology; structural and molecular biology; cancer biology and metabolism; immunity and molecular pathogenesis; molecular and cellular neuroscience; plant molecular and cell biology; and omics, system biology, and synthetic biology. CR is recognized as China's best international journal in life sciences and is part of Springer Nature's prestigious family of Molecular Cell Biology journals.
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