Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries

IF 50 1区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Nature Medicine Pub Date : 2025-01-06 DOI:10.1038/s41591-024-03345-4
Laura Lara-Castor, Meghan O’Hearn, Frederick Cudhea, Victoria Miller, Peilin Shi, Jianyi Zhang, Julia R. Sharib, Sean B. Cash, Simon Barquera, Renata Micha, Dariush Mozaffarian, Global Dietary Database
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Abstract

The consumption of sugar-sweetened beverages (SSBs) is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). However, an updated and comprehensive assessment of the global burden attributable to SSBs remains scarce. Here we estimated SSB-attributable T2D and CVD burdens across 184 countries in 1990 and 2020 globally, regionally and nationally, incorporating data from the Global Dietary Database, jointly stratified by age, sex, educational attainment and urbanicity. In 2020, 2.2 million (95% uncertainty interval 2.0–2.3) new T2D cases and 1.2 million (95% uncertainty interval 1.1–1.3) new CVD cases were attributable to SSBs worldwide, representing 9.8% and 3.1%, respectively, of all incident cases. Globally, proportional SSB-attributable burdens were higher among men versus women, younger versus older adults, higher- versus lower-educated adults, and adults in urban versus rural areas. By world region, the highest SSB-attributable percentage burdens were in Latin America and the Caribbean (T2D: 24.4%; CVD: 11.3%) and sub-Saharan Africa (T2D: 21.5%; CVD: 10.5%). From 1990 to 2020, the largest proportional increases in SSB-attributable incident T2D and CVD cases were in sub-Saharan Africa (+8.8% and +4.4%, respectively). Our study highlights the countries and subpopulations most affected by cardiometabolic disease associated with SSB consumption, assisting in shaping effective policies and interventions to reduce these burdens globally. Estimates from the Global Dietary Database indicated that 2.2 million new type 2 diabetes and 1.2 million new cardiovascular disease cases were attributable to sugar-sweetened beverages worldwide in 2020, with the highest burdens in sub-Saharan Africa, Latin America and the Caribbean.

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184个国家含糖饮料导致的2型糖尿病和心血管疾病负担
含糖饮料(SSBs)的消费与2型糖尿病(T2D)和心血管疾病(CVD)有关。然而,对可归因于SSBs的全球负担的最新和全面评估仍然很少。在此,我们结合全球饮食数据库的数据,根据年龄、性别、受教育程度和城市化程度进行分层,估计了1990年和2020年全球、区域和国家184个国家由ssb引起的T2D和CVD负担。2020年,全球有220万例(95%不确定区间为2.0-2.3)新发T2D病例和120万例(95%不确定区间为1.1-1.3)新发CVD病例可归因于SSBs,分别占所有病例的9.8%和3.1%。在全球范围内,男性比女性、年轻人比老年人、受教育程度较高的成年人比受教育程度较低的成年人以及城市地区比农村地区的成年人的ssb比例负担更高。按世界区域划分,拉丁美洲和加勒比的ssb可归因负担百分比最高(T2D: 24.4%;心血管疾病:11.3%)和撒哈拉以南非洲(心血管疾病:21.5%;心血管疾病:10.5%)。从1990年到2020年,撒哈拉以南非洲地区因ssb引起的T2D和CVD病例的比例增幅最大(分别为+8.8%和+4.4%)。我们的研究强调了受与SSB消费相关的心脏代谢疾病影响最大的国家和亚人群,有助于制定有效的政策和干预措施,以减轻全球的这些负担。
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来源期刊
Nature Medicine
Nature Medicine 医学-生化与分子生物学
CiteScore
100.90
自引率
0.70%
发文量
525
审稿时长
1 months
期刊介绍: Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.
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