Divide and conquer, mitochondrial edition: Subpopulations direct cellular energy and nutrient supply

IF 27.7 1区 生物学 Q1 CELL BIOLOGY Cell metabolism Pub Date : 2025-01-07 DOI:10.1016/j.cmet.2024.12.006
Sijie Tan, Nora Kory
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引用次数: 0

Abstract

Mitochondria produce energy and building blocks essential for cell growth. How these competing processes are balanced and sustained during nutrient scarcity remains unclear. Ryu et al. uncover distinct mitochondrial subpopulations, one dedicated to ATP production and another to macromolecule synthesis, enabling cell growth and proliferation under nutrient-limiting conditions.
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分而治之,线粒体版:亚种群直接细胞能量和营养供应
线粒体产生细胞生长所必需的能量和基础材料。在营养缺乏的情况下,这些相互竞争的过程是如何平衡和维持的尚不清楚。Ryu等人发现了不同的线粒体亚群,一个致力于ATP的产生,另一个致力于大分子的合成,使细胞在营养限制的条件下生长和增殖。
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来源期刊
Cell metabolism
Cell metabolism 生物-内分泌学与代谢
CiteScore
48.60
自引率
1.40%
发文量
173
审稿时长
2.5 months
期刊介绍: Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.
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