Tao Ma, Hao Gao, Jun Wu, Jintao Zhao, Bingbing Chang, Zhibin Zhang, Shengxiang Zhang, Baoxin Zhang, Jianguo Fang
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引用次数: 0
Abstract
A fluorescence quenching mechanism using linear diselenides was proposed for the first time through a combination of intramolecular charge transfer (ICT) and Förster resonance energy transfer (FRET). Herein, we synthesized and screened a two-photon fluorescent probe AFC-SeSe, demonstrating a remarkable 300-fold increase in response to glutathione (GSH). Additionally, AFC-SeSe enabled real-time observation of increased thiol levels following treatment within a short timeframe in a mouse model of stroke.
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