Central Nervous System Tumor-Embryonal Tumors Type With Neuroendocrine Differentiation.

IF 9.6 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical Nuclear Medicine Pub Date : 2025-04-01 Epub Date: 2024-12-30 DOI:10.1097/RLU.0000000000005655
Yeshwanth Edamadaka, Rahul V Parghane, Sandip Basu
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Abstract

Abstract: The central nervous system (CNS) tumor with embryonal tumors type is a rare type of CNS tumor with lack of unifying genetic alterations or diagnostic markers. The CNS tumor-embryonal tumors (CETs) have limited therapeutic options with high probability of adverse events associated with conventional treatment. Identification of somatostatin receptor expression and/or prostate-specific membrane antigen expression in CET patients by using PET/CT imaging may be helpful for deciding therapeutic approaches in these patients as theranostics. We present a 56-year-old woman who complained of headache, diminution of vision, and diagnosed CET and demonstrated high SSTR expression on PET/CT imaging, indicating peptide receptor radionuclide therapy could be effective therapeutic option in this case.

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中枢神经系统肿瘤-胚胎肿瘤类型与神经内分泌分化。
摘要:胚胎型中枢神经系统(CNS)肿瘤是一种罕见的中枢神经系统肿瘤,缺乏统一的遗传改变或诊断标记。中枢神经系统肿瘤-胚胎性肿瘤(cts)的治疗选择有限,与常规治疗相关的不良事件的概率很高。利用PET/CT成像技术鉴定CET患者的生长抑素受体表达和/或前列腺特异性膜抗原表达可能有助于确定这些患者的治疗方法。我们报告了一位56岁的女性,主诉头痛,视力下降,诊断为CET, PET/CT显示高SSTR表达,提示肽受体放射性核素治疗可能是这种情况下有效的治疗选择。
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来源期刊
Clinical Nuclear Medicine
Clinical Nuclear Medicine 医学-核医学
CiteScore
2.90
自引率
31.10%
发文量
1113
审稿时长
2 months
期刊介绍: Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.
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