Efficacy and Safety of 730-nm Picosecond Laser for the Treatment of Acquired Bilateral Nevus of Ota-like Macules.

IF 2.5 3区医学 Q2 DERMATOLOGY Dermatologic Surgery Pub Date : 2025-01-07 DOI:10.1097/DSS.0000000000004545

Rui Han, Yifang Sun, Mingshan Su

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Abstract

Background: The effectiveness and safety of 730-nm picosecond laser for treating acquired bilateral nevus of Ota-like macules remain uncertain.

Objective: This study aims to evaluate the potential benefits and risks of using the 730-nm picosecond laser for ABNOM removal.

Methods: This is a retrospective review of patients who were presented to the clinic between January 2020 and January 2024 for the treatment of ABNOM with 730-nm picosecond laser alone. The efficacy of the laser was assessed based on the Quartile Improvement Scale, using high-resolution photographs evaluated by blinded dermatologists.

Results: A total of 72 Chinese participants with Fitzpatrick skin types III to IV were included in the study. The overall effective rate of the treatment was 75%, achieved after an average of 2.42 ± 0.75 sessions. A subgroup analysis of 41 patients who completed 3 treatment sessions showed statistically significant differences in outcomes across the sessions. The mean improvement scores for sessions 1, 2, and 3 were 1.63 ± 1.04, 2.66 ± 1.22, and 3.29 ± 1.17, respectively (p < .01). No cases of hypopigmentation were observed. The incidence of postinflammatory hyperpigmentation was 5.56%.

Conclusion: The 730-nm picosecond laser is a safe and effective treatment for ABNOM in Chinese patients.

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730nm皮秒激光治疗获得性双侧奥塔样斑痣的疗效和安全性。

背景：730nm皮秒激光治疗获得性双侧奥塔样痣的有效性和安全性尚不确定。目的：本研究旨在评价730nm皮秒激光去除ABNOM的潜在益处和风险。方法：回顾性分析2020年1月至2024年1月间接受730nm皮秒激光单独治疗ABNOM的患者。激光的疗效根据四分位数改善量表进行评估，使用由盲法皮肤科医生评估的高分辨率照片。结果：共有72名菲茨帕特里克皮肤III型至IV型的中国参与者被纳入研究。治疗的总有效率为75%，平均2.42±0.75个疗程后达到。完成3个疗程的41名患者的亚组分析显示，疗程的结果有统计学上的显著差异。第1、2、3期的平均改善评分分别为1.63±1.04、2.66±1.22、3.29±1.17 （p < 0.01）。没有观察到色素减退的病例。炎症后色素沉着的发生率为5.56%。结论：皮秒激光治疗ABNOM是一种安全有效的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dermatologic Surgery 医学-皮肤病学

CiteScore

3.10

自引率

16.70%

发文量

547

期刊介绍： Exclusively devoted to dermatologic surgery, the Dermatologic Surgery journal publishes the most clinically comprehensive and up-to-date information in its field. This unique monthly journal provides today’s most expansive and in-depth coverage of cosmetic and reconstructive skin surgery and skin cancer through peer-reviewed original articles, extensive illustrations, case reports, ongoing features, literature reviews and correspondence. The journal provides information on the latest scientific information for all types of dermatologic surgery including: -Ambulatory phlebectomy- Blepharoplasty- Body contouring- Chemical peels- Cryosurgery- Curettage and desiccation- Dermabrasion- Excision and closure- Flap Surgery- Grafting- Hair restoration surgery- Injectable neuromodulators- Laser surgery- Liposuction- Microdermabrasion- Microlipoinjection- Micropigmentation- Mohs micrographic surgery- Nail surgery- Phlebology- Sclerotherapy- Skin cancer surgery- Skin resurfacing- Soft-tissue fillers. Dermatologists, dermatologic surgeons, plastic surgeons, oculoplastic surgeons and facial plastic surgeons consider this a must-read publication for anyone in the field.

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