{"title":"Successful pain control of lymphangioma-suspected lesions in pregnancy with acetaminophen and opioids: A case report and literature review","authors":"Haruna Kawatani, Takashi Shibata, Fumikazu Kotsuji, Hiroki Kato, Shigeki Nishikawa, Satoshi Nakago","doi":"10.1111/jog.16208","DOIUrl":null,"url":null,"abstract":"<p>Lymphangioma causing pain during pregnancy is not widely reported, but surgical treatment was performed in each of the reported cases. In our patient, lesions arose in the retroperitoneal cavity and caused intense pain from 17 weeks of gestation. However, surgical treatment was considered difficult because of the location of the lesion. The maximum dose of acetaminophen was administered, but pain relief remained unsatisfactory, and there were concerns about possible side effects of long-term use of high-dose acetaminophen on the fetus. Following attempts to control pain and reduce the acetaminophen dose, adding opioids was effective in controlling the pain and minimizing both dosages as much as possible. The patient was able to continue her pregnancy to term, avoiding highly invasive surgery during pregnancy. The combination of acetaminophen and opioids is reported here as an alternative treatment option to surgical procedures for intense pain caused by lesions such as lymphangioma in pregnancy.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 1","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Obstetrics and Gynaecology Research","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jog.16208","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Lymphangioma causing pain during pregnancy is not widely reported, but surgical treatment was performed in each of the reported cases. In our patient, lesions arose in the retroperitoneal cavity and caused intense pain from 17 weeks of gestation. However, surgical treatment was considered difficult because of the location of the lesion. The maximum dose of acetaminophen was administered, but pain relief remained unsatisfactory, and there were concerns about possible side effects of long-term use of high-dose acetaminophen on the fetus. Following attempts to control pain and reduce the acetaminophen dose, adding opioids was effective in controlling the pain and minimizing both dosages as much as possible. The patient was able to continue her pregnancy to term, avoiding highly invasive surgery during pregnancy. The combination of acetaminophen and opioids is reported here as an alternative treatment option to surgical procedures for intense pain caused by lesions such as lymphangioma in pregnancy.
期刊介绍:
The Journal of Obstetrics and Gynaecology Research is the official Journal of the Asia and Oceania Federation of Obstetrics and Gynecology and of the Japan Society of Obstetrics and Gynecology, and aims to provide a medium for the publication of articles in the fields of obstetrics and gynecology.
The Journal publishes original research articles, case reports, review articles and letters to the editor. The Journal will give publication priority to original research articles over case reports. Accepted papers become the exclusive licence of the Journal. Manuscripts are peer reviewed by at least two referees and/or Associate Editors expert in the field of the submitted paper.