Serum 25(OH) Vitamin D Concentrations in Horses: Effects of Age, Gender, Breed, Skin Colour and Season.

IF 1.8 3区农林科学 Q2 VETERINARY SCIENCES Veterinary Medicine and Science Pub Date : 2025-01-01 DOI:10.1002/vms3.70092

Mohieddin Alemi, Saba Ahmadi Sheikhsarmast, Mehrdad Mohri

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Abstract

Background: The optimal amount of vitamin D required for the proper functioning of the immune system differs from the amount necessary for bone homeostasis. Furthermore, vitamin D metabolism varies among horses. Nevertheless, there is a dearth of information regarding reference values for vitamin D in horses, particularly in the Turkmen breed. The primary objectives of this study were to determine the concentrations of 25-hydroxyvitamin D (25(OH)Vit D) in Turkmen, Thoroughbred and mixed Turkmen × Thoroughbred horses and to explore the effects of various factors on it and its relationship with serum biochemical variables and signalment data.

Methods: For the measurement of 25(OH)Vit D, 90 healthy horses (min age: 6 months; max age: 10 years) that were stable in the north of Iran (37°17' N, 55°18' E) were selected for clinical examination and complete blood biochemistry analysis. The horses were categorised into different groups based on sex, season (spring, n = 45; autumn, n = 45), breed (Turkmen, Thoroughbred and mixed Turkmen × Thoroughbred), age (< 2 years, 2-8 years and > 8 years) and skin colour. Sampling was performed only once from each horse.

Results: In this study, the median serum concentration of 25(OH)Vit D in the sampled horses was 17.42 ng/mL (IQR: 9.82-30.85). The serum 25(OH)Vit D concentration was significantly lower in autumn (median: 15.83 ng/mL and IQR: 8.67-54.68) than in spring (median: 18.02 ng/mL and IQR: 13.77-27.54) and was also lower in Turkmen horses (median: 15.83 ng/mL and IQR: 11.63-23.12) than in mixed breed horses (median: 17.72 ng/mL and IQR: 8.94-51.67) (p ≤ 0.05).

Conclusion: According to the results of the present study, the season had a significant effect on the serum 25(OH)Vit D concentration, and this difference was also observed between Turkmen horses and mixed-bred horses (p ≤ 0.05). It is unclear whether the time of sun exposure or vitamin D content of diet causes the seasonal difference of 25(OH)Vit D concentration.

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马血清25（OH）维生素D浓度：年龄、性别、品种、肤色和季节的影响

背景：免疫系统正常运作所需的维生素D的最佳量不同于骨骼稳态所需的量。此外，不同马的维生素D代谢也不同。然而，缺乏关于马，特别是土库曼品种中维生素D参考值的信息。本研究的主要目的是测定土库曼、纯种马和土库曼×纯种马体内25（OH）维生素D （25(OH)Vit D）的浓度，探讨各种因素对其的影响及其与血清生化指标和信号数据的关系。方法：测定健康马90匹(最小年龄6个月；选取生活在伊朗北部（北纬37°17′，东经55°18′）的稳定患者进行临床检查和完整的血液生化分析。根据马的性别、季节(春季，n = 45；秋季，n = 45)，品种（土库曼，纯种马和混合土库曼×纯种马），年龄（8岁）和肤色。每匹马只进行一次采样。结果：本研究中，样本马血清25(OH)Vit D的中位浓度为17.42 ng/mL （IQR: 9.82 ~ 30.85）。秋季血清25(OH)Vit D浓度（中位数：15.83 ng/mL, IQR: 8.67 ~ 54.68）显著低于春季（中位数：18.02 ng/mL, IQR: 13.77 ~ 27.54），土库曼马血清25(OH)Vit D浓度（中位数：15.83 ng/mL, IQR: 11.63 ~ 23.12）显著低于混合马（中位数：17.72 ng/mL, IQR: 8.94 ~ 51.67）（p≤0.05）。结论：根据本研究结果，季节对血清25(OH)Vit D浓度有显著影响，土库曼马与杂交马之间也存在差异（p≤0.05）。目前尚不清楚25（OH）维生素D浓度的季节差异是由日照时间还是饮食中维生素D含量引起的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary Medicine and Science Veterinary-General Veterinary

CiteScore

3.00

自引率

0.00%

发文量

296

期刊介绍： Veterinary Medicine and Science is the peer-reviewed journal for rapid dissemination of research in all areas of veterinary medicine and science. The journal aims to serve the research community by providing a vehicle for authors wishing to publish interesting and high quality work in both fundamental and clinical veterinary medicine and science. Veterinary Medicine and Science publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper. We aim to be a truly global forum for high-quality research in veterinary medicine and science, and believe that the best research should be published and made widely accessible as quickly as possible. Veterinary Medicine and Science publishes papers submitted directly to the journal and those referred from a select group of prestigious journals published by Wiley-Blackwell. Veterinary Medicine and Science is a Wiley Open Access journal, one of a new series of peer-reviewed titles publishing quality research with speed and efficiency. For further information visit the Wiley Open Access website.