Is ADDM graft practical? A comparative study to evaluate ADDM graft in third molar surgery.

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2025-01-09 DOI:10.1007/s10006-025-01332-8

Aashita Jain, D S Gupta, Nandakishore Donepudi, Saubhagya S Agrawal, Deepika Saini, Pooja Bijarniya

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Abstract

Background: It has been outlined that LTM (Lower third molar) extracted from patients in which grinding, cleaning, sterilization & demineralization prove to be highly effective as graft material for filling the alveolar socket of the very same patient. These investigations aim to assess the efficiency of ADDM (Autogenous Demineralized Dentin Matrix) graft in third molar extraction sockets.

Purpose: To check the effectiveness of ADDM as graft material in extraction socket by evaluating pain, swelling, trismus, PD (Probing Depth) and bone density.

Study design, setting, sample: A prospective, randomized control trial was conducted at our institute. The patients were haphazardly, non-blindly alienated into two groups. Group A (45 patients) on the test side after LTM impaction surgery will receive ADDM graft material with bio-collagen membrane and Group B (45 patients) on the control side underwent LTM removal, with the alveolus left to heal conventionally by forming a blood clot.

Results: Swelling showed significant difference between CG (Control Group) and TG (Test Group), the intergroup comparison of change in the swelling scores at seventh post-operative day (from pre-op level) was significantly higher in the TG (117.35) as compared to the CGs (115.92) (p = 0.001). A statistically significant difference in probing depth was also noted between the two groups, CG 4.46 ± 1.252 & TG 2.52 ± 0.641 in the post-operative examination at three months. In our study radiographical evaluation revealed progressive increase in bone density in TG (135.81 ± 8.73) when compared to CG (121.59 ± 13.83) over a period of three months. Pain and trismus evaluation did not reveal any significant difference between TG & CG.

Conclusion: The clinical results of the ADDM graft procedure demonstrate satisfactory outcomes in extraction sockets. The findings of this study highlight the importance of preservation methods in maintaining the periodontal pocket depth distal to the second molar and the remaining alveolar ridge following extraction.

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ADDM移植实用吗？第三磨牙手术中ADDM移植的比较研究。

背景：已经概述了从患者身上提取的LTM（下第三磨牙），经过研磨，清洁，灭菌和脱矿证明是非常有效的移植物材料，用于填充同一患者的牙槽窝。本研究旨在评估自体脱矿牙本质基质（ADDM）移植在第三磨牙拔牙槽中的效果。目的：通过对拔牙槽疼痛、肿胀、咬合、PD （Probing Depth）及骨密度的评价，探讨ADDM作为植牙材料在拔牙槽内的有效性。研究设计、环境、样本：本研究为前瞻性、随机对照试验。这些病人被随机地、非盲目地分成两组。试验侧LTM嵌塞术后A组（45例）接受带生物胶原膜的ADDM移植物材料，对照组B组（45例）接受LTM去除，保留肺泡常规形成血凝块愈合。结果：TG组（对照组）与TG组（试验组）肿胀评分差异有统计学意义，TG组（117.35分）术后第7天肿胀评分变化组间比较差异有统计学意义（p = 0.001）； TG组（115.92分）术后第7天肿胀评分差异有统计学意义（p = 0.001）。两组术后3个月探查深度分别为CG（4.46±1.252）、TG(2.52±0.641)，差异有统计学意义。在我们的研究中，x线评估显示，在三个月的时间里，TG的骨密度（135.81±8.73）比CG（121.59±13.83）逐渐增加。疼痛和牙关评估在TG和CG之间没有明显差异。结论：ADDM移植治疗拔牙槽疗效满意。本研究结果强调了保存方法在拔牙后维持第二磨牙远端牙周袋深度和剩余牙槽嵴的重要性。

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来源期刊

Oral and Maxillofacial Surgery-Heidelberg DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.20

自引率

5.60%

发文量

118

期刊介绍： Oral & Maxillofacial Surgery founded as Mund-, Kiefer- und Gesichtschirurgie is a peer-reviewed online journal. It is designed for clinicians as well as researchers.The quarterly journal offers comprehensive coverage of new techniques, important developments and innovative ideas in oral and maxillofacial surgery and interdisciplinary aspects of cranial, facial and oral diseases and their management. The journal publishes papers of the highest scientific merit and widest possible scope on work in oral and maxillofacial surgery as well as supporting specialties. Practice-oriented articles help improve the methods used in oral and maxillofacial surgery.Every aspect of oral and maxillofacial surgery is fully covered through a range of invited review articles, clinical and research articles, technical notes, abstracts, and case reports. Specific topics are: aesthetic facial surgery, clinical pathology, computer-assisted surgery, congenital and craniofacial deformities, dentoalveolar surgery, head and neck oncology, implant dentistry, oral medicine, orthognathic surgery, reconstructive surgery, skull base surgery, TMJ and trauma.Time-limited reviewing and electronic processing allow to publish articles as fast as possible. Accepted articles are rapidly accessible online.Clinical studies submitted for publication have to include a declaration that they have been approved by an ethical committee according to the World Medical Association Declaration of Helsinki 1964 (last amendment during the 52nd World Medical Association General Assembly, Edinburgh, Scotland, October 2000). Experimental animal studies have to be carried out according to the principles of laboratory animal care (NIH publication No 86-23, revised 1985).